Factors associated with patients' knowledge of and attitudes towards treatment with lithium
Factors associated with patients' knowledge of and attitudes towards treatment with lithium
复制标题
DOI：
10.1016/s0165-0327(02)00027-7
复制
发表时间：
2003-06-01
影响因子：
6.6
通讯作者：
Eagles, JM
中科院分区：
文献类型：
--
作者：
Dharmendra, MS;Eagles, JM
背景资料：锂盐治疗通常因依从性差、副作用和患者血清水平超出治疗范围而受到影响。这些因素可能会受到患者对锂的知识和态度的影响，我们着手在大量有代表性的患者样本中建立与锂的知识和态度相关的因素。方法：1995年期间在格兰扁服用锂的患者在1998年期间接受了锂知识测试（LKT）和锂态度问卷（LAQ）的调查。通过逐步多元回归分析这些指标的评分与患者的社会人口学和临床特征。结果：在742例患者中，411例（55%）完成了LKT，362例（49%）完成了LAQ。逐步多元回归分析表明，LAQ中对锂的积极态度与较高的血清锂水平（P = 0.005）和持续服用锂（P < 0.001）相关。对LKT的了解越多，对LAQ的态度越积极（P = 0.002），年龄越小（P < 0.001），治疗持续时间越短（P = 0.01）。局限性：本研究是回顾性的，应答率相对较低。结论：关于锂的教育可能对老年人特别重要，对于那些长期服用锂的人来说，“复习课程”是明智的。改变态度的干预措施，而不是提高知识，可能有助于促进遵守。(C)2002 Elsevier Science B.V.保留所有权利。
Background: Treatment with lithium is often compromised by poor adherence, by side-effects and by patients' having serum levels outside the therapeutic range. These factors may be affected by patients' knowledge and attitudes towards lithium, and we set out to establish factors associated with knowledge about and attitudes towards lithium among a large representative sample of patients. Method: Patients known to be taking lithium in Grampian during 1995 were surveyed postally during 1998 with the Lithium Knowledge Test (LKT) and the Lithium Attitudes Questionnaire (LAQ). Scores on these measures were analysed against patients' sociodemographic and clinical characteristics by stepwise multiple regression. Results: Of 742 patients, 411 (55%) completed an LKT and 362 (49%) completed an LAQ. Stepwise multiple regression established that positive attitudes towards lithium on the LAQ were associated with higher serum lithium levels (P = 0.005) and with continuing to take lithium (P < 0.001). Higher knowledge on the LKT was associated with positive attitudes on the LAQ (P = 0.002), with younger age (P < 0.001), and with shorter duration of treatment (P = 0.01) Limitations: The study was retrospective and the response rate was relatively low. Conclusions: Education about lithium is likely to be of particular importance in the elderly and 'refresher courses' are advisable for those who have been on lithium for lengthy periods. Interventions which modify attitudes, rather than enhancing knowledge, are likely to be helpful in promoting adherence. (C) 2002 Elsevier Science B.V. All rights reserved.