PREDICTING SURVIVAL IN BILATERAL BREAST-CARCINOMA

PREDICTING SURVIVAL IN BILATERAL BREAST-CARCINOMA
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DOI:
10.1111/j.1445-2197.1989.tb01462.x
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发表时间:
1989-01-01
期刊:
AUSTRALIAN AND NEW ZEALAND JOURNAL OF SURGERY
影响因子:
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通讯作者:
HOLDAWAY, I
HOLDAWAY, I
中科院分区:
其他
文献类型:
--
作者:
ALEXANDER, AI;MERCER, RJ;HOLDAWAY, I

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研究了38例双侧乳腺癌患者的生存率。肿瘤是同步的14例和异时的24。生存率低于先前开发的指数,包括淋巴结状态,雌激素受体含量,孕激素受体含量和患者年龄的基础上预测的肿瘤。两种肿瘤指数的简单相加给出了一个更好的预测因子,尽管这也夸大了同步性和异时性肿瘤的生存前景。因此,这一经验表明,同时性或异时性双侧乳腺癌患者的生存前景很差,比合理预期的要差。
Survival in 38 patients with bilateral breast cancer has been studied. The tumours were synchronous in 14 patients and metachronous in 24. Survival was less than that predicted for either tumour on the basis of a previously developed index involving lymph node status, oestrogen receptor content, progesterone receptor content, and patient age. Simple addition of the indices for the two tumours gave a better predictor although this also overstated the prospects for survival for both synchronous and metachronous tumours. This experience suggests, therefore, that the prospects of survival for patients with synchronous or metachronous bilateral breast carcinoma is poor, and worse than might reasonably be anticipated.