The relationship between trait vulnerability and anxiety and depressive diagnoses at long-term follow-up of Generalized Anxiety Disorder
The relationship between trait vulnerability and anxiety and depressive diagnoses at long-term follow-up of Generalized Anxiety Disorder
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DOI：
10.1016/j.janxdis.2003.09.001
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发表时间：
2004-01-01
影响因子：
10.3
通讯作者：
Durham, RC
中科院分区：
文献类型：
--
作者：
Chambers, JA;Power, KG;Durham, RC
本研究探讨了83例广泛性焦虑症（GAD）患者8-14年前诊断和治疗的特质脆弱性和长期结果之间的关系。采用结构化访谈评估诊断状况，采用积极与消极情感量表（PANAS）、状态-特质焦虑量表（STAI-T）和个人风格量表（PSI）分别测量特质情感、特质焦虑和特质抑郁。特质测量都是高度相关的，在长期随访中诊断为广泛性焦虑症、社交恐怖症和抑郁症的患者在所有三个量表上的得分都很差。治疗前记录的特质焦虑也与长期随访时的焦虑和抑郁相关。然而，特质抑郁症与惊恐障碍没有显着关联。共病诊断的增加与高水平的特质焦虑和负性情感（NA）密切相关。研究结果表明，报告高特质焦虑或NA的患者可能患有慢性疾病，并且在较长时间内合并症水平较高。(C)2003年爱思唯尔公司All rights reserved.
The current study examined the relationship between measures of trait vulnerability and long-term outcome in 83 patients diagnosed and treated for Generalized Anxiety Disorder (GAD) 8-14 years previously. Diagnostic status was assessed by structured interview, and trait affect, trait anxiety and trait depression were measured by the Positive and Negative Affect Scale (PANAS), the State-Trait Anxiety Inventory (STAI-T) and the Personal Style Inventory (PSI), respectively. Trait measures were all highly inter-correlated, and patients with diagnoses of GAD, social phobia and depressive disorders at long-term follow-up recorded very poor scores on all three scales. Trait anxiety recorded pre-treatment was also related to both anxiety and depression at long-term follow-up. However, trait depression showed no significant association with panic disorder. Increased numbers of comorbid diagnoses were strongly related to high levels of both trait anxiety and negative affect (NA). The findings suggest that patients reporting high trait anxiety or NA may suffer from a chronic course of disorder and higher levels of comorbidity over the longer term. (C) 2003 Elsevier Inc. All rights reserved.