Longitudinal MRI Evaluation of Ischemic Stroke in the Basal Ganglia of a Rhesus Macaque (Macaca mulatta) with Seizures
Longitudinal MRI Evaluation of Ischemic Stroke in the Basal Ganglia of a Rhesus Macaque (Macaca mulatta) with Seizures
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DOI：
10.30802/aalas-cm-18-000004
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发表时间：
2018-12-01
影响因子：
0.8
通讯作者：
Zhang, Xiaodong
中科院分区：
文献类型：
--
作者：
Li, Chun-Xia;Kempf, Doty J.;Zhang, Xiaodong
一只成年恒河猴在诱发缺血性中风后出现癫痫发作。最初，在手术当天，局灶性缺血性损害仅存在于右侧尾状核。在卒中诱导后48小时，当观察到癫痫发作时，病变已经延伸到壳核。我们的报告强调了急性卒中后单侧基底节梗塞的时间变化和伴随的临床症状。考虑到以前的病例报告和研究通常没有在临床症状出现之前描述病变的时间和空间演变，这一不寻常的病例可能提供有关基底神经节参与癫痫发作的额外信息。
An adult rhesus macaque developed seizures after the induction of ischemic stroke. Initially, on the day of surgery, a focal ischemic lesion was present exclusively in the right caudate nucleus. By 48 h after stroke induction, the lesion had extended into the putamen, when a seizure was observed. Our report highlights the temporal changes in infarction of unilateral basal ganglia after acute stroke and the accompanying clinical symptoms. This unusual case may provide additional information regarding the involvement of the basal ganglia in seizures, given that prior case reports and studies usually have not described the temporal and spatial evolution of the lesion before clinical symptoms emerge.