Tumor functional and molecular imaging utilizing ultrasound and ultrasound-mediated optical techniques.
Tumor functional and molecular imaging utilizing ultrasound and ultrasound-mediated optical techniques.
复制标题
利用超声和超声介导的光学技术进行肿瘤功能和分子成像。
DOI：
10.1016/j.ajpath.2012.07.036
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发表时间：
2013
期刊：
影响因子：
--
通讯作者：
Rychak,Joshua
中科院分区：
文献类型：
--
作者：
Yuan,Baohong;Rychak,Joshua
肿瘤功能成像和分子成像为肿瘤临床前研究和临床应用做出了重要贡献。在典型的成像方式中，超声和光学技术是两种常用的方法;两者都具有几个共同的特征，例如成本效率、不存在电离辐射、相对便宜的造影剂和可比的最大成像深度。超声和光学技术在成像分辨率、分子灵敏度和成像空间（血管和血管外）方面也是互补的。超声波和光学技术之间的结合利用了这两种技术的优点。本文综述了利用微泡超声和超声介导的光学成像技术进行肿瘤功能和分子成像。
Tumor functional and molecular imaging has significantly contributed to cancer preclinical research and clinical applications. Among typical imaging modalities, ultrasonic and optical techniques are two commonly used methods; both share several common features such as cost efficiency, absence of ionizing radiation, relatively inexpensive contrast agents, and comparable maximum-imaging depth. Ultrasonic and optical techniques are also complementary in imaging resolution, molecular sensitivity, and imaging space (vascular and extravascular). The marriage between ultrasonic and optical techniques takes advantages of both techniques. This review introduces tumor functional and molecular imaging using microbubble-based ultrasound and ultrasound-mediated optical imaging techniques.