RISK-FACTORS FOR ESOTROPIA AND EXOTROPIA
RISK-FACTORS FOR ESOTROPIA AND EXOTROPIA
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DOI：
10.1001/archopht.1994.01090220099030
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发表时间：
1994-10-01
影响因子：
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通讯作者：
KLEBANOFF, M
中科院分区：
文献类型：
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作者：
CHEW, E;REMALEY, NA;KLEBANOFF, M
目的：为了确定与两种主要类型的斜视-内斜视和外斜视-在一个队列的儿童随访从怀孕到7岁years.Design：孕妇参加了合作项目的国家研究所神经疾病和中风，贝塞斯达，马里兰州，从1959年至1965年在12所大学中心。这项大型多学科研究旨在评估妊娠期和围产期并发症的发育后果。通过医学检查和访谈，收集了39227名儿童及其母亲的母亲、社会经济、围产期和新生儿特征的数据。检查的儿童进行了出生时，4个月，8个月，1年，7 years.Outcome Measures：在后续检查中进行斜视的存在的评价，并确认在7年的随访访视。结果：1187名儿童发生内斜视（3.0%），490名儿童发生外斜视（1.2%）。内斜视在白人中更常见（白人3.9%对黑人2.2%，P
Objective: To identify risk factors associated with the two major types of strabismus-esotropia and exotropia-in a cohort of children followed up from gestation to age 7 years.Design: Pregnant women were enrolled in the Collaborative Project of the National Institute of Neurological Disorders and Stroke, Bethesda, Md, from 1959 to 1965 at 12 university centers. This large multidisciplinary study was designed to evaluate the developmental consequences of complications during pregnancy and the perinatal period. Data on maternal, socioeconomic, perinatal, and neonatal characteristics were collected from 39 227 children and their mothers by medical examination and interview. Examinations of the children were performed at birth, 4 months, 8 months, 1 year, and 7 years.Outcome Measures: The evaluation of the presence of strabismus was performed during follow-up examinations and confirmed at the 7-year follow-up visit. Potential risk factors for strabismus were evaluated from the maternal, socioeconomic, perinatal, and neonatal characteristics.Results: Esotropia developed in 1187 children (3.0%), and exotropia developed in 490 children (1.2%). Esotropia was more common in whites (3.9% in whites vs 2.2% in blacks, P