Total thyroidectomy for multinodular goiter in the elderly
Total thyroidectomy for multinodular goiter in the elderly
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DOI：
10.1016/j.amjsurg.2005.03.029
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发表时间：
2005-09-01
影响因子：
3
通讯作者：
Lo, CY
中科院分区：
文献类型：
--
作者：
Lang, BHH;Lo, CY
工作背景：全甲状腺切除术治疗多结节性甲状腺肿（MNG）越来越多地用于老年人群，但其围手术期和长期结局仍不清楚。方法：根据手术时的年龄，对一所大学医院9年期间接受全甲状腺切除术治疗MNG的279例患者进行分析。结果：手术时间（P = .023），术中失血量（P = .030），切除的甲状腺重量胸骨后甲状腺肿的比例（P < .001）（P < .001）在老年组（≥ 70岁）（n = 55）中显著更高，但手术相关并发症（包括喉返神经麻痹和甲状旁腺功能减退）的发生率相似。老年组术后肺炎发生率更高（P = .034）。合并症的数量往往与住院时间和长期生存在老年patients.Conclusions：甲状腺全切除术MNG在老年患者有一个类似的围手术期的结果，他们的年轻同行，但他们的长期结果是可能受到影响的合并症的数量。(c)2005 Excerpta Medica Inc. All rights reserved.
Background: Total thyroidectomy for multinodular goiter (MNG) is increasingly being performed for the elderly population and yet their perioperative and long-term outcomes remain unclear.Methods: A total of 279 patients who underwent total thyroidectomy for MNG in a university-based hospital during a 9-year period were analyzed according to their age at the time of operation.Results: The duration of operation (P = .023), intraoperative blood loss (P = .030), weight of resected thyroid glands (P < .001) and proportion of retrosternal goiter (P < .001) were significantly greater in the elderly group (>= 70 years) (n = 55), but the incidence of surgically related complications, including recurrent laryngeal nerve palsy and hypoparathyroidism, was similar. Postoperative pneumonia occurred more frequently in the elderly group (P = .034). The number of comorbidities tended to correlate with the length of hospital stay and long-term survival in elderly patients.Conclusions: Total thyroidectomy for MNG in elderly patients had a similar perioperative outcome as their younger counterparts, but their long-term outcome is likely to be influenced by the number of comorbidities. (c) 2005 Excerpta Medica Inc. All rights reserved.