A single amino acid substitution in the virus-encoded replicase of tomato mosaic tobamovirus alters host specificity
A single amino acid substitution in the virus-encoded replicase of tomato mosaic tobamovirus alters host specificity
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DOI：
10.1094/mpmi.1997.10.8.1015
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发表时间：
1997-11-01
影响因子：
3.5
通讯作者：
Okada, Y
中科院分区：
文献类型：
--
作者：
Hamamoto, H;Watanabe, Y;Okada, Y
引入一个单一的氨基酸取代（Gln 979到Ile）到130-和180-kDa的蛋白质的番茄花叶病毒（ToMV）的突变体几乎无法复制在番茄细胞中，而它在烟草细胞中复制完美。这种变化的主机特异性的机制进行了讨论。
Introduction of a single amino acid substitution (Gln979 to Ile) into the 130- and 180-kDa proteins of tomato mosaic tobamovirus (ToMV) rendered the mutant virtually unable to replicate in tomato cells while it replicated perfectly in tobacco cells. The mechanism of this change in host specificity is discussed.