An ancestral signalling pathway is conserved in intracellular symbioses-forming plant lineages
An ancestral signalling pathway is conserved in intracellular symbioses-forming plant lineages
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DOI：
10.1038/s41477-020-0613-7
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发表时间：
2020-03-02
期刊：
影响因子：
18
通讯作者：
Delaux, Pierre-Marc
中科院分区：
文献类型：
--
作者：
Radhakrishnan, Guru V.;Keller, Jean;Delaux, Pierre-Marc
植物是陆地生态系统的基础，它们在陆地上的殖民可能是通过与丛枝菌根真菌的互利共生来促进的。在这一创始事件之后，植物多样化导致了与微生物的互利共生的巨大多样性的出现，从细胞外关联到最亲密的细胞内关联，其中真菌或细菌共生体寄生在植物细胞内。在这里，通过对涵盖整个陆地植物多样性的 271 个转录组和 116 个植物基因组的分析，我们证明了一个共同的共生信号通路与细胞内内共生共同进化，从祖先的丛枝菌根到被子植物中的丛枝菌根和兰花菌根以及苔藓植物的类丛枝菌根。相比之下，仅形成细胞外共生的物种，例如外生菌根，以及与蓝藻形成关联的物种，已经失去了这种信号通路。这项工作统一了细胞内共生，揭示了 4.5 亿年来植物多样化进化中的保守性。基于数百个基因组和转录组的广泛系统发育组学研究为陆地植物中不同类型的共生关联的进化提供了新的解释，并揭示了保守的祖先共生途径。
Plants are the foundation of terrestrial ecosystems, and their colonization of land was probably facilitated by mutualistic associations with arbuscular mycorrhizal fungi. Following this founding event, plant diversification has led to the emergence of a tremendous diversity of mutualistic symbioses with microorganisms, ranging from extracellular associations to the most intimate intracellular associations, where fungal or bacterial symbionts are hosted inside plant cells. Here, through analysis of 271 transcriptomes and 116 plant genomes spanning the entire land-plant diversity, we demonstrate that a common symbiosis signalling pathway co-evolved with intracellular endosymbioses, from the ancestral arbuscular mycorrhiza to the more recent ericoid and orchid mycorrhizae in angiosperms and ericoid-like associations of bryophytes. By contrast, species forming exclusively extracellular symbioses, such as ectomycorrhizae, and those forming associations with cyanobacteria, have lost this signalling pathway. This work unifies intracellular symbioses, revealing conservation in their evolution across 450 million yr of plant diversification.An extensive phylogenomics study based on hundreds of genomes and transcriptomes provides a new interpretation of the evolution of different types of symbiotic associations in land plants, and reveals a conserved ancestral symbiosis pathway.