FcγRIIa genotype predicts progression of HIV infection

FcγRIIa genotype predicts progression of HIV infection
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DOI:
10.4049/jimmunol.179.11.7916
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发表时间:
2007-12-01
影响因子:
4.4
通讯作者:
Montoya, Benjamin
Montoya, Benjamin
中科院分区:
医学2区
文献类型:
--
作者:
Forthal, Donald N.;Landucci, Gary;Montoya, Benjamin

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Fc γ R基因多态性与许多自身免疫性和感染性疾病的易感性或严重性相关。我们发现,在多中心艾滋病队列研究中,Fc γ RIIa RR基因型的HIV感染男性的CD4(+)细胞计数进展为
Polymorphisms in Fc gamma R genes are associated with susceptibility to or severity of a number of autoimmune and infectious diseases. We found that HIV-infected men in the Multicenter AIDS Cohort Study with the Fc gamma RIIa RR genotype progressed to a CD4(+) cell count of