Improved Semiautomated 4D Flow MRI Analysis in the Aorta in Patients With Congenital Aortic Valve Anomalies Versus Tricuspid Aortic Valves.
Improved Semiautomated 4D Flow MRI Analysis in the Aorta in Patients With Congenital Aortic Valve Anomalies Versus Tricuspid Aortic Valves.
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DOI：
10.1097/rct.0000000000000312
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发表时间：
2016-01
影响因子：
1.3
通讯作者：
Markl M
中科院分区：
文献类型：
--
作者：
Schnell S;Entezari P;Mahadewia RJ;Malaisrie SC;McCarthy PM;Collins JD;Carr J;Markl M
To systematically investigate a newly developed semi-automated workflow for the analysis of aortic 4D-flow MRI and its ability to detect hemodynamic differences in patients with congenitally altered aortic valve (CAV, bicuspid or quadricuspid valves) compared to tricuspid aortic valves (TAV). 4D-flow MRI data were acquired in 20 aortic dilation patients (9 TAV, 11 CAV). A semi-automated workflow was evaluated regarding inter-observer variability, accuracy of net flow, regurgitant fraction and peak systolic velocity, and the ability to detect differences between cohorts. Results were compared to manual segmentation of vessel contours. Despite the significantly reduced analysis time a good inter-observer agreement was found for net flow and peak systolic velocity and moderate agreement for regurgitation. Significant differences in peak velocities in the descending aorta (P=0.014) could be detected. 4D-flow MRI-based semi-automated analysis of aortic hemodynamics can be performed with good reproducibility and accuracy.
