Bacteriocin (mutacin) production by Streptococcus mutans genome sequence reference strain UA159:: Elucidation of the antimicrobial repertoire by genetic dissection
Bacteriocin (mutacin) production by Streptococcus mutans genome sequence reference strain UA159:: Elucidation of the antimicrobial repertoire by genetic dissection
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DOI：
10.1128/aem.71.11.7613-7617.2005
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发表时间：
2005-11-01
影响因子：
4.4
通讯作者：
Heng, NCK
中科院分区：
文献类型：
--
作者：
Hale, JDF;Ting, YT;Heng, NCK
变异链球菌UA159，基因组序列参考菌株，显示非羊毛硫抗生素突变素活性。在这项研究中，采用生物信息学和突变分析来证明菌株UA159的抗菌谱包括突变蛋白IV（由nlm位点指定）和新鉴定的细菌素突变蛋白V（由SMU.1914c编码）。
Streptococcus mutans UA159, the genome sequence reference strain, exhibits nonlantibiotic mutacin activity. In this study, bioinformatic and mutational analyses were employed to demonstrate that the antimicrobial repertoire of strain UA159 includes mutacin IV (specified by the nlm locus) and a newly identified bacteriocin, mutacin V (encoded by SMU.1914c).