Polyphenols, antioxidants, and antimutagenic effects of Copaifera langsdorffii fruit
Polyphenols, antioxidants, and antimutagenic effects of Copaifera langsdorffii fruit
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DOI：
10.1016/j.foodchem.2015.11.093
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发表时间：
2016-04-15
期刊：
影响因子：
8.8
通讯作者：
Marostica Junior, Mario Roberto
中科院分区：
文献类型：
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作者：
Batista, Angela Giovana;Ferrari, Angelica Simoes;Marostica Junior, Mario Roberto
Copaifera langsdorffii（copaiba）是巴西的一种外来水果，关于其生物活性成分的研究很少。本研究的目的是确定的生物活性成分，抗氧化和抗突变活性的柯派芭果肉。用不同溶剂提取样品，以分析多酚化合物（Folin Ciocalteau和HPLC-DAD），总黄酮（与AlCl 3反应）和抗氧化能力（FRAP，ORAC，DPPH）。咖啡果多酚含量高，抗氧化能力强。在苦配巴果肉中鉴定出酚类化合物，如没食子酸、表儿茶素没食子酸酯、儿茶素、表儿茶素和异槲皮苷。尽管具有抗氧化能力，但最高剂量的copaiba在体内研究中没有显示出抗突变作用。显示抗突变活性的剂量为100 mg/kg。(C)2015由Elsevier Ltd.出版
Copaifera langsdorffii (copaiba) is a Brazilian exotic fruit, poorly studied regarding its bioactive composition. The aim of this study was to determine bioactive compounds, antioxidant and antimutagenic activities of copaiba pulp. The samples were extracted with different solvents in order to analyze polyphenol compounds (Folin Ciocalteau and HPLC-DAD), total flavonoids (reaction with AlCl3) and antioxidant capacity (FRAP, ORAC, DPPH). The copaiba fruit showed high polyphenol content and antioxidant capacity. Phenolic compounds, such as gallic acid, epicatechin gallate, catechin, epicatechin and isoquercitrin, were identified in the copaiba pulp. Despite the antioxidant capacity, the highest dose of copaiba showed no antimutagenic effects in the in vivo study. The dose which showed antimutagenic activity was 100 mg kg(-1). (C) 2015 Published by Elsevier Ltd.