Pineal gland biorhythms: N-acetyltransferase in chickens and rats.
Pineal gland biorhythms: N-acetyltransferase in chickens and rats.
复制标题
松果体生物节律：鸡和大鼠的 N-乙酰转移酶。
DOI：
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发表时间：
1976
期刊：
影响因子：
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通讯作者：
S. Binkley
中科院分区：
文献类型：
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作者：
S. Binkley
在松果体中参与血清素代谢的化学因素中已经确定了昼夜节律。本文综述了环境光照下脊椎动物的节律特征及其调控。特别强调了大鼠和鸡松果体n -乙酰转移酶活性的节律。这种节律不仅在某些鸟类和哺乳动物的明暗循环中很明显，在持续的黑暗中也会持续存在。在恒定的光线下，节奏消失了。光的作用是通过老鼠的眼睛，但鸡的视网膜外光感受器参与其中。n -乙酰转移酶活性节律的细节包括暗时酶活性上升的不应期和高暗时活性被光快速关闭的存在。在鸡体内，n -乙酰转移酶时钟可以用一段时间的恒定光照来重置。大鼠节律的神经调节涉及视交叉上核和颈上神经节；在鸡中，神经节对明暗循环的节律不是必需的，视交叉上核尚未被研究。
Circadian rhythms have been identified in chemical factors involved in the metabolism of serotonin in the pineal gland. The rhythms are reviewed with respect to their characteristics and regulation by environmental lighting in vertebrates. Special emphasis has been given to the rhythm in pineal N-acetyltransferase activity in rats and chickens. This rhythm is not only apparent in a light-dark cycle in some birds and mammals, it also persists in constant dark. In constant light the rhythm is lost. The action of light is via the eyes in rats but extraretinal photoreceptors are involved in chickens. The details of the N-acetyltransferase activity rhythm include the presence of a refractory period for the rise in dark-time enzyme activity and the rapid turnoff of high dark-time activity by light. The N-acetyltransferase clock can be reset with a period of constant light in the chicken. Neural regulation of the rhythm in rats involves the suprachiasmatic nucleus and the superior cervical ganglion; in chickens, the ganglion is not necessary for the rhythm in light-dark cycles and the suprachiasmatic nucleus has not been studied.