Yield strain behavior of trabecular bone
Yield strain behavior of trabecular bone
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DOI：
10.1016/s0021-9290(98)00057-8
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发表时间：
1998-07-01
影响因子：
2.4
通讯作者：
Keaveny, TM
中科院分区：
文献类型：
--
作者：
Kopperdahl, DL;Keaveny, TM
如果骨适应维持恒定的应变，如果骨小梁的轴向屈服应变与表观密度无关，那么骨小梁的适应性重塑应在习惯性加载时保持恒定的安全系数（屈服应变/功能应变）。为了验证屈服应变确实与密度无关的假设，对低密度（0.18 +/- 0.04 g cm(-3)）人椎小梁骨标本进行了无末端伪影的压缩（n = 22）和拉伸（n = 22）屈服应变测量。载荷沿主小梁方向上下方向施加。将这些“轴上”屈服菌株与先前测量的高密度（0.51 +/- 0.06 g cm(-3)）牛胫骨小梁骨（n = 44）的屈服菌株进行比较。人骨的平均+/- sd)屈服应变在拉伸时为0.78 +/- 0.04%，在压缩时为0.84 +/- 0.06%；牛骨的对应值分别为0.78 +/- 0.04和1.09 +/- 0.12%。在整个密度范围内，拉伸屈服应变与表观密度无关（人p = 0.40，牛p = 0.64，池p = 0.97）。相比之下，压缩屈服应变与人骨表观密度呈线性相关（p < 0.001），合并数据（p < 0.001），牛数据存在暗示趋势（p = 0.06）。这些结果驳斥了小梁骨的轴向屈服应变与压缩载荷的密度无关的假设，尽管值可能在狭窄的密度范围内呈现恒定。轴向拉伸屈服应变似乎与表观密度和解剖部位无关。1998爱思唯尔科学有限公司版权所有。
If bone adapts to maintain constant strains and if on-axis yield strains in trabecular bone are independent of apparent density, adaptive remodeling in trabecular bone should maintain a constant safety factor (yield strain/functional strain) during habitual loading. To test the hypothesis that yield strains are indeed independent of density, compressive (n = 22) and tensile (n = 22) yield strains were measured without end-artifacts for low density (0.18 +/- 0.04 g cm(-3)) human vertebral trabecular bone specimens. Loads were applied in the superior-inferior direction along the principal trabecular orientation. These 'on-axis' yield strains were compared to those measured previously for high-density (0.51 +/- 0.06 g cm(-3)) bovine tibial trabecular bone (n = 44). Meant +/- S.D.) yield strains for the human bone were 0.78 +/- 0.04% in tension and 0.84 +/- 0.06% in compression; corresponding values for the bovine bone were 0.78 +/- 0.04 and 1.09 +/- 0.12%, respectively. Tensile yield strains were independent of the apparent density across the entire density range (human p = 0.40, bovine p = 0.64, pooled p = 0.97). By contrast, compressive yield strains were linearly correlated with apparent density for the human bone (p < 0.001) and the pooled data (p < 0.001), and a suggestive trend existed for the bovine data (p = 0.06). These results refute the hypothesis that on-axis yield strains for trabecular bone are independent of density for compressive loading, although values may appear constant over a narrow density range. On-axis tensile yield strains appear to be independent of both apparent density and anatomic site. (C) 1998 Elsevier Science Ltd. All rights reserved.