Endophthalmitis therapy: changing antibiotic sensitivity patterns and current therapeutic recommendations.
Endophthalmitis therapy: changing antibiotic sensitivity patterns and current therapeutic recommendations.
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眼内炎治疗:改变抗生素敏感性模式和当前的治疗建议。
DOI:
10.1001/archopht.1991.01080020021012
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发表时间:
1991
影响因子:
--
通讯作者:
D. Miller
中科院分区:
文献类型:
--
作者:
H. Flynn;J. Pulido;S. Pflugfelder;J. Davis;W. Culbertson;T. J. Roussel;D. Miller
To the Editor. —Martin and associates 1 reported vitreous cefazolin levels in a rabbit model of experimental endophthalmitis. These authors used heat-killed Staphylococcus epidermidis organisms to induce intraocular inflammation and then measured the penetration of systemically administered cefazolin. Meredith and associates 2 reported further rabbit model studies of S epidermidis endophthalmitis and observed no significant difference in inflammatory scores between the placebo-treated group and the group treated with 2.25 mg of intravitreal cefazolin. However, there were more eyes with clear media at the end of week 3 in the group treated with vitrectomy, 2.25 mg of intravitreal cefazolin, and either systemic or intravitreal corticosteroids. Although cefazolin does penetrate the eye from systemic administration and also may be used intravitreally, it is important to recognize that frequent resistance will occur among organisms commonly encountered in clinical endophthalmitis. Davis and associates 3 reported a series of cases of coagulase-negative staphylococci with a 19%
DOI:
10.1001/archopht.1990.01070050109043
发表时间:
1990
期刊:
Archives of ophthalmology (Chicago, Ill. : 1960)
影响因子:
--
作者:
Martin,DF;Ficker,LA;Aguilar,HA;Gardner,SK;Wilson,LA;Meredith,TA
通讯作者:
Meredith,TA
DOI:
10.1001/archopht.1990.01070080101043
发表时间:
1990
期刊:
Archives of ophthalmology (Chicago, Ill. : 1960)
影响因子:
--
作者:
Meredith,TA;Aguilar,HE;Miller,MJ;Gardner,SK;Trabelsi,A;Wilson,LA
通讯作者:
Wilson,LA
影响因子:
4.4
作者:
Ficker,L;Meredith,TA;Gardner,S;Wilson,LA
通讯作者:
Wilson,LA