The descriptive epidemiology of Streptococcus pneumoniae and Haemophilus influenzae nasopharyngeal carriage in children and adults in Kilifi district, Kenya
The descriptive epidemiology of Streptococcus pneumoniae and Haemophilus influenzae nasopharyngeal carriage in children and adults in Kilifi district, Kenya
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DOI：
10.1097/inf.0b013e31814da70c
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发表时间：
2008-01-01
影响因子：
3.6
通讯作者：
Scott, J. Anthony G.
中科院分区：
文献类型：
--
作者：
Abdullahi, Osman;Ayiro, Joyce;Scott, J. Anthony G.
背景资料：传播和鼻咽定植是侵袭性肺炎球菌或流感嗜血杆菌疾病的必要步骤，但其模式在地理上各不相同。在东非，我们不知道这些病原体是如何传播的人口亚群之间，也没有哪种血清型circulates.Methods：我们做了2个横截面鼻咽拭子调查随机选择受试者从人口登记估计患病率和风险因素，在2004年进行。H. 2001年引进B型流感疫苗。结果：在旱季采样的450人中，414人在雨季重新采样。在0-4岁、5-9岁和10-85岁的受试者中，肺炎球菌携带率分别为57%、41%和6.4%。H.流感流行率分别为26%、24%和3.0%。H.儿童B型流感
Background: Transmission and nasopharyngeal colonization are necessary steps en route to invasive pneumococcal or Haemophilus influenzae disease but their patterns vary geographically. In East Africa we do not know how these pathogens are transmitted between population subgroups nor which serotypes circulate commonly.Methods: We did 2 cross-sectional nasopharyngeal swab surveys selecting subjects randomly from a population register to estimate prevalence and risk-factors for carriage in 2004. H. influenzae type b vaccine was introduced in 2001.Results: Of 450 individuals sampled in the dry season, 414 were resampled during the rainy season. Among subjects 0-4, 5-9, and 10-85 years old pneumococcal carriage prevalence was 57%, 41%, and 6.4%, respectively. H. influenzae prevalence was 26%, 24%, and 3.0%, respectively. Prevalence of H. influenzae type b in children