EOCYTES - A NEW RIBOSOME STRUCTURE INDICATES A KINGDOM WITH A CLOSE RELATIONSHIP TO EUKARYOTES
EOCYTES - A NEW RIBOSOME STRUCTURE INDICATES A KINGDOM WITH A CLOSE RELATIONSHIP TO EUKARYOTES
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DOI：
10.1073/pnas.81.12.3786
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发表时间：
1984-01-01
期刊：
影响因子：
--
通讯作者：
CLARK, MW
中科院分区：
文献类型：
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作者：
LAKE, JA;HENDERSON, E;CLARK, MW
核糖体大小亚基以4种一般结构模式组织。这4种类型分别存在于真细菌、古细菌、真核生物和一组依赖硫的细菌（原细胞）的核糖体中。所有4种核糖体类型都有一个共同的结构核心，但每种类型也有额外的独立结构特征。独立的特征包括真核生物的裂片和较小亚基上的古细菌喙。在较大的亚基上，它们包括eocytic叶、eocytic间隙和eocytic隆起以及修饰的中央突起。这些数据是最简约地适合一个单一的，无根的进化树。在这棵树中，真细胞与真核生物密切相关：古细菌和真细菌是最接近的邻居。该树与目前已知的分子生物学特性是一致的，并表明eocytes具有系统发育的重要性等于3个已知的王国。当这些生物体的其他特性和分子机制被更好地定义时，这个群体的适当界名可能是Eocyta。
Ribosomal large and small subunits are organized in 4 general structural patterns. The 4 types are found in ribosomes from eubacteria, archaebacteria, eukaryotes and a group of S-dependent bacteria (eocytes), respectively. All 4 ribosomal types share a common structural core, but each type also has additional independent structural features. The independent features include the eukaryotic lobes and the archaebacterial bill on the smaller subunit. On the larger subunit, they include the eocytic lobe, eocytic gap and eocytic bulge and a modified central protuberance. These data are most parsimoniously fit by a single, unrooted evolutionary tree. In this tree, eocytes are closely related to eukaryotes: archaebacteria and eubacteria are closest neighbors. The tree is consistent with currently known molecular biological properties and indicates that eocytes have a phylogenetic importance equal to that of the 3 known kingdoms. When other properties and molecular mechanisms of these organisms are better defined, an appropriate kingdom name for this group might be the Eocyta.