An Excised Canine Model of Anterior Glottic Web and Its Acoustic, Aerodynamic, and High-speed Measurements.
An Excised Canine Model of Anterior Glottic Web and Its Acoustic, Aerodynamic, and High-speed Measurements.
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DOI：
10.1016/j.jvoice.2016.08.006
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发表时间：
2017-03
期刊：
影响因子：
--
通讯作者：
Jiang J
中科院分区：
文献类型：
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作者：
Xue C;Pulvermacher A;Calawerts W;Devine E;Jiang J
本研究旨在建立离体前声门（AGW）模型，并通过研究前声门的声学、空气动力学和振动特性来研究前声门的基本发声机制。总体而言，对使用的8只犬喉中的每一只进行了4种条件测试。在基线、10%、20%和33%闭塞（根据缝线位置确定）时，收集声学、空气动力学和高速视频数据，同时在隔音室中发声。随着阻塞率的增加，发声阈压（PTP）和发声阈流量显著增加（P < 0.001）。在PTP、1.25 PTP和1.5 PTP时，从基线组到AGW模型组，抖动%和闪烁%显著增加（分别为P = 0.039、P <0.001、P <0.001、P <0.001和P = 0.001）。在所有给定压力下，随着闭塞百分比的增加，基频显著增加（P < 0.001）。在PTP、1.25 PTP和1.5 PTP时，AGW模型组的关联维数（D2）显著高于基线组（P = 0.002，P < 0.001，P = 0.01）。在高速视频中，AGW模型组在1.25 PTP与基线相比的左相移是显著的（P = 0.027），在1.5 PTP与基线相比的右相移是显著的（P < 0.001）。我们提出了一个解剖学上类似的1型AGW模型，并通过空气动力学，声学和高速视频分析，在我们的研究中证实了其有效性。我们观察和研究了声门蹼的运动，这可能是一个新的解释的病理语音相关机制AGW。
This study aims to build an excised anterior glottic web (AGW) model and study the basic voice-related mechanisms of the AGW through investigating the acoustic, aerodynamic, and vibratory properties. Overall, four conditions were tested for each of the eight canine larynges used. At baseline, 10%, 20%, and 33% occlusion (as determined by the placement of the suture), acoustic, aerodynamic, and high-speed video data were collected while each larynx was phonated in a soundproof booth. The phonation threshold pressure (PTP) and the phonation threshold flow significantly increased as percent occlusion increased (P < 0.001). There were significant increases in jitter % and shimmer % from baseline group to AGW model groups at PTP, 1.25 PTP, and 1.5 PTP (P = 0.039, P < 0.001, P < 0.001, P < 0.001, P < 0.001, and P = 0.001, respectively). The fundamental frequency significantly increased as percent occlusion increased at all given pressures (P < 0.001). Correlation dimension (D2) was significantly higher in the AGW model groups than in the baseline group at PTP, 1.25 PTP, and 1.5 PTP (P = 0.002, P < 0.001, P = 0.01, respectively). In high-speed videos, the left phase shift in the AGW model groups compared with the baseline at 1.25 PTP was significant (P = 0.027) and right phase shift at 1.5 PTP (P < 0.001). We presented an anatomically similar model of a type 1 AGW and confirmed its validity through aerodynamic, acoustic, and high-speed video analysis in our study. We observed and investigated the glottic web movement, which may be a new explanation for the pathologic voice-related mechanism of AGW.