EEG Signatures of Dynamic Functional Network Connectivity States.
EEG Signatures of Dynamic Functional Network Connectivity States.
复制标题
动态功能网络连接状态的EEG签名。
DOI：
10.1007/s10548-017-0546-2
复制
发表时间：
2018-01
期刊：
影响因子：
2.7
通讯作者：
Calhoun VD
中科院分区：
文献类型：
--
作者：
Allen EA;Damaraju E;Eichele T;Wu L;Calhoun VD
人类大脑通过动态调节不同的神经群体来实现目标导向行为。不同脑区之间的同步或缺乏同步被认为对应于在静息状态脑成像数据中观察到的功能连接动态。在一个大样本的健康人类成年受试者，并利用滑动窗口相关方法的功能成像数据，我们证明了存在七个不同的功能连接状态/模式之间的不同的大脑网络，可靠地发生跨时间和主题。这些连接状态是否对应于有意义的电生理特征尚不清楚。在这项研究中，使用一个数据集与并发EEG和静息状态的功能成像数据采集在眼睛睁开和闭上眼睛的状态下，我们证明了以前的研究结果在一个独立的样本的可复制性，并确定与这些功能网络连接的变化相关的EEG频谱特征。睁眼和闭眼条件显示与不同EEG频谱特征相关的共同和不同的连接模式。某些连接状态在眼睛睁开的情况下更普遍，而一些连接状态仅在眼睛闭合状态下发生。这两种情况都表现出与EEG频谱α功率降低和δ和θ功率增加相关的丘脑皮质电活动关系增加的状态，这可能反映了困倦。这种状态在眼睛闭合状态下更频繁地发生。总之，我们发现动态连接功能磁共振成像数据和同时收集的脑电图数据之间的联系，包括一个很大的影响警惕功能连接。正如EEG和fMRI所证明的那样，即使在相对较短的时间内，也不能假设连接的稳定性。
The human brain operates by dynamically modulating different neural populations to enable goal directed behavior. The synchrony or lack thereof between different brain regions is thought to correspond to observed functional connectivity dynamics in resting state brain imaging data. In a large sample of healthy human adult subjects and utilizing a sliding windowed correlation method on functional imaging data, earlier we demonstrated the presence of seven distinct functional connectivity states/patterns between different brain networks that reliably occur across time and subjects. Whether these connectivity states correspond to meaningful electrophysiological signatures was not clear. In this study, using a dataset with concurrent EEG and resting state functional imaging data acquired during eyes open and eyes closed states, we demonstrate the replicability of previous findings in an independent sample, and identify EEG spectral signatures associated with these functional network connectivity changes. Eyes open and eyes closed conditions show common and different connectivity patterns that are associated with distinct EEG spectral signatures. Certain connectivity states are more prevalent in the eyes open case and some occur only in eyes closed state. Both conditions exhibit a state of increased thalamocortical anticorrelation associated with reduced EEG spectral alpha power and increased delta and theta power possibly reflecting drowsiness. This state occurs more frequently in the eyes closed state. In summary, we find a link between dynamic connectivity in fMRI data and concurrently collected EEG data, including a large effect of vigilance on functional connectivity. As demonstrated with EEG and fMRI, the stationarity of connectivity cannot be assumed, even for relatively short periods.
登录
查看更多内容
影响因子：
5.7
作者：
Bianciardi M;Fukunaga M;van Gelderen P;Horovitz SG;de Zwart JA;Duyn JH
通讯作者：
Duyn JH
大脑网络的时尚表征：融合并发的EEG光谱和fMRI图。
影响因子：
5.7
作者：
Bridwell DA;Wu L;Eichele T;Calhoun VD
通讯作者：
Calhoun VD
影响因子：
4.3
作者：
Gonzalez-Castillo J;Handwerker DA;Robinson ME;Hoy CW;Buchanan LC;Saad ZS;Bandettini PA
通讯作者：
Bandettini PA
影响因子：
3.7
作者：
Allen, Elena A.;Damaraju, Eswar;Calhoun, Vince D.
通讯作者：
Calhoun, Vince D.
影响因子：
--
作者：
Chang, Che-Jung;Li, Der-Chiang;Chen, Chien-Chih
通讯作者：
Chen, Chien-Chih