Peripapillary capillary vessel density progression in advanced glaucoma: a case report
Peripapillary capillary vessel density progression in advanced glaucoma: a case report
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DOI：
10.1186/s12886-018-1021-x
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发表时间：
2019-01-05
影响因子：
2
通讯作者：
Hollo, Gabor
中科院分区：
文献类型：
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作者：
Hollo, Gabor
我们报道了一例晚期青少年开角型青光眼(JOAG)，其下视网膜乳头周围毛细血管密度(PcVD)显著增加，而相应的视网膜神经纤维层厚度(RNFlt)和视野簇缺陷值已达到其最小可检测值，并且在随访期间(地板效应)没有变化。病例介绍对一名45岁的左眼正在接受JOAG治疗的晚期白人女性患者进行了前瞻性研究(AngioVue OCT，Optovue Inc.，PcVD)和Octopus G2正常视野测试，每隔6个月进行6次访问。图像质量高(5次8/10，1次7/10)，光学介质清晰。视网膜上、下基线值分别为48和43m，PcVD值分别为28.9和36.5%。用该仪器进行线性回归分析，差异有统计学意义(P
BackgroundWe report a case of advanced juvenile open-angle glaucoma (JOAG) in which peripapillary capillary vessel density (PcVD) in the inferior retina showed significant progression while the spatially corresponding retinal nerve fiber layer thickness (RNFLT) and visual field cluster defect values had reached their minimal detectable values, and showed no change during the follow-up (floor effect).Case presentationA 45-year old white female patient with very advanced under treatment JOAG in the left eye was prospectively investigated with the AngioVue OCT (Optovue Inc., Fremont, USA) for RNFLT and PcVD, and Octopus Normal G2 visual field testing, at 6-month intervals for 2.5years (6 visits). Images quality was high (8/10 in 5 visits and 7/10 in one visit), and the optical media were clear. For the superior and inferior retina the baseline RNFLT and PcVD values were 48 and 43m, and 28.9 and 36.5%, respectively. Using the instrument's linear regression analysis significant progression (P