Multiple biological activities of curcumin: A short review

Multiple biological activities of curcumin: A short review
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DOI:
10.1016/j.lfs.2005.12.007
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发表时间:
2006-03-27
期刊:
影响因子:
6.1
通讯作者:
Srimal, RC
Srimal, RC
中科院分区:
医学2区
文献类型:
--
作者:
Maheshwari, RK;Singh, AK;Srimal, RC

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Turmieric(Curcuma longa rhizomes),通常用作香料,在印度和中国的医学系统中有很好的药用价值。它已被广泛用于治疗多种疾病。流行病学的观察,虽然不确定,但表明姜黄消费可能会降低某种形式的癌症的风险,并在人类中产生其他保护性生物效应。姜黄的这些生物学作用归因于其成分姜黄素,姜黄素因其抗炎,抗血管生成,抗氧化,伤口愈合和抗癌作用而被广泛研究。作为广泛的流行病学,临床和动物研究的结果,一些分子机制正在出现,阐明姜黄素的多种生物学效应。本文综述了姜黄素生物学效应的体外和体内研究进展。爱思唯尔公司出版
Turmieric (Curcuma longa rhizomes), commonly used as a spice is well documented for its medicinal properties in Indian and Chinese systems of medicine. It has been widely used for the treatment of several diseases. Epidemiological observations, though inconclusive, are suggestive that turmeric consumption may reduce the risk of some form of cancers and render other protective biological effects in humans. These biological effects of turmeric have been attributed to its constituent curcumin that has been widely studied for its anti-inflammatory, anti-angiogenic, antioxidant, wound healing and anti-cancer effects. As a result of extensive epidemiological, clinical, and animal studies several molecular mechanisms are emerging that elucidate multiple biological effects of curcumin. This review summarizes the most interesting in vitro and ill vivo studies on the biological effects of curcumin. Published by Elsevier Inc.