Load dependency measurement of IPS cell-derived cardiomyocytes' contraction
Load dependency measurement of IPS cell-derived cardiomyocytes' contraction
复制标题
IPS 细胞来源的心肌细胞收缩的负荷依赖性测量
DOI：
10.1109/memsys.2018.8346500
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发表时间：
2018
期刊：
影响因子：
--
通讯作者：
I. Shimoyama
中科院分区：
文献类型：
--
作者：
Kenei Matsudaira;Hidetoshi Takahashi;Kayoko Hirayama Shoji;Thanh;T. Tsukagoshi;I. Shimoyama
在本文中，我们提出了一种方法来评估抽搐力和静态拉伸刺激的iPS细胞衍生的心肌细胞（iPSC-CMs）（力-长度关系）之间的关系。该方法实现了在培养条件下静态拉伸iPSC-CM的收缩力测量。结果，测量到几十μ N的抽搐力，并且随着静态拉伸的增加观察到抽搐力的变化。
In this paper, we propose a method to evaluate relationships between twitch forces and static stretch stimuli of iPS cell-derived cardiomyocytes (iPSC-CMs) (force-length relation). The method realized the twitch force measurement of iPSC-CMs statically stretched under the culturing condition. As a result, twitch forces of a few tens of μΝ were measured, and the variation of twitch forces was observed as the static stretch was increased.