Manometric evaluation of esophageal-protective reflexes in infants and children

Manometric evaluation of esophageal-protective reflexes in infants and children
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DOI:
10.1016/s0002-9343(03)00215-8
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发表时间:
2003-08-18
影响因子:
5.9
通讯作者:
Jadcherla, SR
Jadcherla, SR
中科院分区:
医学2区
文献类型:
--
作者:
Jadcherla, SR

文献摘要

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在成年人中,食管运动。响应促进吞咽期间的向前或反口运输,并在食团的逆行运动期间保护呼吸消化道,这可能发生在胃食管反流的情况下。儿科文献中尚不清楚婴儿在这些事件中是否激活了适当的食管运动防御反应。因此,本研究研究了婴儿在基础状态和食管刺激时的食管运动反应。使用水灌注测压技术和一个特殊设计的测压导管,3可能的机制,可以保护呼吸消化道被确认:继发性水肿,食管上食管括约肌收缩反射,食管吞咽反应。(C)2003年,Excerpta Medica,Inc.
In adults, esophageal motor. responses facilitate forward, or aboral, transit during swallowing, and protect the aerodigestive tract during retrograde movement of the bolus, which may occur with gastroesophageal reflux. It is unclear in the pediatric literature whether the activation of appropriate esophageal motor defense responses occurs during these events in infants. This investigation therefore studied the esophageal motor responses during the basal state and upon esophageal stimulation in infants. Using the water-perfusion manometry technique and a specially designed manometric catheter, 3 likely mechanisms that may protect the aerodigestive tract were recognized: secondary peristalsis, esophago-upper esophageal sphincter contractile reflex, and esophagodeglutition response. (C) 2003 by Excerpta Medica, Inc.