Effects of Lifetime History of Use of Problematic Alcohol on HIV Medication Adherence.
Effects of Lifetime History of Use of Problematic Alcohol on HIV Medication Adherence.
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DOI：
10.1177/2325957413491430
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发表时间：
2014-09-01
影响因子：
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通讯作者：
Jones, Deborah
中科院分区：
文献类型：
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作者：
Sharma, Aman;Sachdeva, Ravinder Kaur;Jones, Deborah
BACKGROUND: The effects of previous alcohol abuse on antiretroviral therapy (ART) adherence have been less studied.MATERIALS AND METHODOLOGY: Participants were randomized to a 3-month group intervention or an individual-enhanced standard-of-care condition and assessed over 6 months. Individual assessment at baseline, 3, and 6 months was done; interviews included lifetime history of problematic alcohol use.RESULTS: A total of 80 HIV-positive individuals on ART were recruited. In all, 35% of participants reported a history of problematic alcohol use, 37% had a detectable viral load, 55% were nonadherent, and 24% reporting skipping medication in the previous 3 months. There was no association between a history of problematic use and an adherence at any time point, that is, at baseline (t = -.7, P = .47), midpoint (t = -.39, P = .69), and 6-month follow-up (t = -1.2, P = .23).CONCLUSION: Results suggest that a history of problematic alcohol use may not impact ART adherence.
