Performance of the OraQuick rapid antibody test for diagnosis of human immunodeficiency virus type 1 infection in patients with various levels of exposure to highly active antiretroviral therapy
Performance of the OraQuick rapid antibody test for diagnosis of human immunodeficiency virus type 1 infection in patients with various levels of exposure to highly active antiretroviral therapy
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DOI：
10.1128/jcm.41.5.2153-2155.2003
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发表时间：
2003-05-01
影响因子：
9.4
通讯作者：
De Witt, CC
中科院分区：
文献类型：
--
作者：
O'Connell, RJ;Merritt, TM;De Witt, CC
用101名人类免疫缺陷病毒1型(HIV-1)感染者和100名HIV-1阴性志愿者的口腔黏膜漏出液和血清样本，OraQuick HIV-1检测显示出100%的特异性和96%的敏感性。4名假阴性受试者的特征是早期开始有效的抗逆转录病毒治疗，他们的血清抗gp41效价和Western印迹条带强度都在减弱。
With oral mucosal transudate and serum samples from 101 human immunodeficiency virus type 1 (HIV-1)-infected subjects and 100 HIV-1-negative volunteers, the OraQuick HIV-1 test demonstrated 100% specificity and 96% sensitivity. Four false-negative subjects, who were characterized by early initiation of effective antiretroviral therapy, demonstrated waning serum anti-gp41 titers and Western blot band intensities.