Long-term plasticity in adult somatosensory cortex: functional reorganization after surgical removal of an arteriovenous malformation.
Long-term plasticity in adult somatosensory cortex: functional reorganization after surgical removal of an arteriovenous malformation.
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成人体感皮层的长期可塑性：动静脉畸形手术切除后的功能重组。
DOI：
10.1080/13554794.2014.960429
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发表时间：
2015
期刊：
影响因子：
0.8
通讯作者：
Savage,Greg
中科院分区：
文献类型：
--
作者：
Burianová,Hana;Rich,AninaN;Williams,Mark;Morgan,Michael;Marstaller,Lars;Maruff,Paul;Baker,ChrisI;Savage,Greg
由于神经外科干预导致脑结构急性改变后神经可塑性的时间尺度仍在争论中。我们进行了一项纵向研究，目的是调查一名接受脑血管手术的患者术后的变化，该患者随后失去了右手手指的本体感觉。结果表明，增加激活对侧病变的躯体感觉区，额外招聘的运动前区和后顶叶区，并与左中央后回的功能连接的变化。这些发现表明了大脑皮层组织的长期变化，因此对脑损伤患者的治疗策略具有重要意义。
The temporal scale of neuroplasticity following acute alterations in brain structure due to neurosurgical intervention is still under debate. We conducted a longitudinal study with the objective of investigating the postoperative changes in a patient who underwent cerebrovascular surgery and who subsequently lost proprioception in the fingers of her right hand. The results show increased activation in contralesional somatosensory areas, additional recruitment of premotor and posterior parietal areas, and changes in functional connectivity with left postcentral gyrus. These findings demonstrate long-term modifications of cortical organization and as such have important implications for treatment strategies for patients with brain injury.