Pelvic normal tissue contouring guidelines for radiation therapy: a Radiation Therapy Oncology Group consensus panel atlas.
Pelvic normal tissue contouring guidelines for radiation therapy: a Radiation Therapy Oncology Group consensus panel atlas.
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DOI：
10.1016/j.ijrobp.2012.01.023
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发表时间：
2012-07-01
影响因子：
7
通讯作者：
Michalski, Jeff M.
中科院分区：
文献类型：
--
作者：
Gay, Hiram A.;Barthold, H. Joseph;O'Meara, Elizabeth;Bosch, Walter R.;El Naqa, Issam;Al-Lozi, Rawan;Rosenthal, Seth A.;Lawton, Colleen;Lee, W. Robert;Sandler, Howard;Zietman, Anthony;Myerson, Robert;Dawson, Laura A.;Willett, Christopher;Kachnic, Lisa A.;Jhingran, Anuja;Portelance, Lorraine;Ryu, Janice;Small, William, Jr.;Gaffney, David;Viswanathan, Akila N.;Michalski, Jeff M.
为放射治疗肿瘤组（RTOG）试验定义男性和女性盆腔正常组织轮廓图谱。一个男性骨盆计算机断层扫描（CT）数据集和一个女性骨盆CT数据集通过图像引导治疗QA中心共享。共有16名放射肿瘤学家参加。在两个CT集中描绘了以下风险器官：肛门、肛门直肠、直肠（胃肠道和泌尿生殖系统定义）、肠NOS（未另行说明）、小肠、大肠和股骨近端。仅在男性组中对以下部位进行了轮廓勾画：膀胱、前列腺、精囊和阴茎球。仅在女性组中对以下部位进行轮廓勾画：子宫、宫颈和卵巢。计算机程序使用二项分布生成95%组一致性轮廓。这些轮廓和定义随后由小组审查并修改。专家组在RTOG试验中对盆腔正常组织轮廓的定义达成了共识，这些标准化名称为：直肠、肛门直肠、小肠、结肠、肠袋、膀胱、子宫颈、附件_R、附件_L、前列腺、精囊、阴茎球、股骨_R和股骨_L。另外两个正常结构，其目的是作为目标，在肛门和直肠癌被定义：肛门直肠Sig和直肠系膜。详细的目标体积轮廓的指导方针和图像进行了讨论。盆腔正常组织轮廓的共识指南已经达成，并可在RTOG网站上以CT图像图谱的形式获得。这将允许在提供盆腔放射的临床试验中统一定义正常组织，并将促进未来正常组织并发症的研究。
To define a male and female pelvic normal tissue contouring atlas for Radiation Therapy Oncology Group (RTOG) trials. One male pelvis computed tomography (CT) data set and one female pelvis CT data set were shared via the Image-Guided Therapy QA Center. A total of 16 radiation oncologists participated. The following organs at risk were contoured in both CT sets: anus, anorectum, rectum (gastrointestinal and genitourinary definitions), bowel NOS (not otherwise specified), small bowel, large bowel, and proximal femurs. The following were contoured in the male set only: bladder, prostate, seminal vesicles, and penile bulb. The following were contoured in the female set only: uterus, cervix, and ovaries. A computer program used the binomial distribution to generate 95% group consensus contours. These contours and definitions were then reviewed by the group and modified. The panel achieved consensus definitions for pelvic normal tissue contouring in RTOG trials with these standardized names: Rectum, AnoRectum, SmallBowel, Colon, BowelBag, Bladder, UteroCervix, Adnexa_R, Adnexa_L, Prostate, SeminalVesc, PenileBulb, Femur_R, and Femur_L. Two additional normal structures whose purpose is to serve as targets in anal and rectal cancer were defined: AnoRectumSig and Mesorectum. Detailed target volume contouring guidelines and images are discussed. Consensus guidelines for pelvic normal tissue contouring were reached and are available as a CT image atlas on the RTOG Web site. This will allow uniformity in defining normal tissues for clinical trials delivering pelvic radiation and will facilitate future normal tissue complication research.
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影响因子：
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作者：
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通讯作者：
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DOI：
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发表时间：
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影响因子：
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作者：
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DOI：
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