Impact of spatial distribution of permethrin-impregnated bed nets on child mortality in rural northern Ghana
Impact of spatial distribution of permethrin-impregnated bed nets on child mortality in rural northern Ghana
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DOI：
10.4269/ajtmh.1998.59.80
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发表时间：
1998-07-01
影响因子：
3.3
通讯作者：
Smith, T
中科院分区：
文献类型：
--
作者：
Binka, FN;Indome, F;Smith, T
在加纳北部农村恶性疟原虫疟疾高发地区进行了一项氯菊酯（杀虫剂）浸渍蚊帐（IIBNS）的随机对照试验，研究了空间分布氯菊酯（杀虫剂）浸渍蚊帐对儿童死亡率的影响。在16,841个高危儿童年期间，6-59个月的儿童中有862人死亡。死亡率随距离卫生设施的远近而增加，但不随距离可确定的按蚊孳生地（水库）的远近而增加。IIBNs的疗效与这些距离无关。IIBNs使用者的死亡率与非使用者的接近程度无关，非使用者和彼此居住较近的使用者的死亡率相似。泊松回归估计，距离最近的IIBNS化合物每100米，非使用者的死亡率增加6.7%，表明杀虫剂保护了附近的非使用者。iibn的高覆盖率可以实现最大的影响，但如果覆盖不完全，iibn的用户可以为不那么幸运的邻居提供一些保护。
Effects of the distribution in space of permethrin (insecticide)-impregnated bed nets (IIBNS) on child mortality were studied in a randomized controlled trial of IIBNs in a an area highly endemic for Plasmodium falciparum malaria in rural northern Ghana. Eight hundred sixty-two deaths occurred among children 6-59 months of age during 16,841 child-years-at-risk. Mortality increased with the distance from health facilities but not with proximity to identifiable anopheline breeding sites (reservoirs). The efficacy of IIBNs was independent of these distances. Mortality in users of IIBNs was independent of the proximity of nonusers, and mortality rates of nonusers and users living close to each other were similar. Poisson regression estimated a 6.7% increase in mortality among nonusers with each 100-m shift away from the nearest compound with IIBNS, indicating that the insecticide protects nearby nonusers. High coverage of IIBNs achieves maximum impact, but users of IIBNs offer some protection to less fortunate neighbors if coverage is incomplete.