Levels and congener profiles of halogenated persistent organic pollutants in human serum and semen at an e-waste area in South China
Levels and congener profiles of halogenated persistent organic pollutants in human serum and semen at an e-waste area in South China
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华南电子垃圾区人血清和精液中卤代持久性有机污染物的含量和同系物谱
DOI：
10.1016/j.envint.2020.105666
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发表时间：
2020
影响因子：
11.8
通讯作者：
Chen Cai-rong
中科院分区：
文献类型：
--
作者：
Yu Yun-jiang;Lin Bi-gui;Qiao Jing;Chen Xi-chao;Chen Wan-le;Li Liang-zhong;Chen Xiao-yan;Yang Liu-yan;Yang Pan;Zhang Guo-zhi;Zhou Xiu-qin;Chen Cai-rong
典型的卤化持久性有机污染物（Hal-POPs）包括多溴二苯醚（PBDEs）、多溴联苯（PBBs）、多氯联苯（PCBs）和二氯二苯基三氯乙烷（DDT），是一组普遍存在的具有内分泌干扰作用的有机污染物。本研究评估了在收集和管理电子废物的华南地区生活/工作的男性体内，特别是精液样本中 Hal-POPs 的积累和同系物特征。结果表明，高暴露组（HEG）中Hal-POP同系物的检出频率和血清浓度均高于低暴露组（LEG）。此外，Hal-POPs 精浆浓度也观察到相同的趋势。同一受试者血清和精液样本中PBDE同系物的平均值、中位数和离散值等分布特征相互一致。但血清样品中PCB同系物的分布特征与精液样品中不同。 BDE153 是血清和精液样本中发现的最丰富的同源物之一；因此，它可以被确定为指示剂 PBDE 同系物。需要进一步研究探索 Hal-POPs 在人类精液和血清样本中的分布机制。
Typical halogenated persistent organic pollutants (Hal-POPs), including polybrominated diphenyl ethers (PBDEs), polybrominated biphenyls (PBBs), polychlorinated biphenyls (PCBs), and dichlorodiphenyltrichloroethane (DDT), are a group of ubiquitous organic pollutants with an endocrine disrupting effect. This study evaluated the accumulation and congener profiles of Hal-POPs in the bodies of men who live/work in areas of South China where electronic wastes are collected and managed, especially in their semen samples. The results show that the detection frequency and serum concentrations of Hal-POP congeners within the high-exposure group (HEG) were higher than those of the low-exposure group (LEG). Furthermore, an identical trend was observed for the seminal plasma concentrations of Hal-POPs. The distribution characteristics, such as their mean, median, and discrete values, of PBDE congeners in serum and semen samples from the same subjects were consistent with each other. However, the distribution characteristics of PCB congeners in serum samples were different from those in semen samples. BDE153 was one of the most abundant congeners found in the serum and semen samples; hence, it can be identified as an indicator PBDE congener. Further research is needed to explore the mechanism of Hal-POPs distribution in human semen and serum samples.