New concept bioceramics composed of octacalcium phosphate (OCP) and dicarboxylic acid-intercalated OCP via hydrothermal hot-pressing
New concept bioceramics composed of octacalcium phosphate (OCP) and dicarboxylic acid-intercalated OCP via hydrothermal hot-pressing
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DOI：
10.1016/j.msec.2009.02.023
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发表时间：
2009-08-01
影响因子：
7.9
通讯作者：
Nakahira, Atsushi
中科院分区：
文献类型：
--
作者：
Ishihara, Shiho;Matsumoto, Takuya;Nakahira, Atsushi
合成了磷酸八钙（OCP）和己二酸插层复合OCP（Adi-OCP）。此外，我们通过水热热压（HHP）方法将它们制成陶瓷体。用X射线衍射仪（XRD）对粉体和陶瓷的特征进行了研究。用扫描电子显微镜（SEM）观察陶瓷的表面形貌。测定了陶瓷的密度、抗压强度和孔径分布。新开发的OCP陶瓷的晶体结构没有从起始材料的相变。此外，新开发的OCP陶瓷只有通过低至110 ℃的HHP处理才具有良好的机械性能。为了评价生物活性，将陶瓷浸泡在模拟体液（SBF）中。预测OCP和Adi-OCP具有比传统HAp陶瓷更好的生物活性。(C)2009爱思唯尔有限公司版权所有。
Octacalcium phosphate (OCP) and adipic acid-intercalated complexed OCP (Adi-OCP) were synthesized. Moreover, we made ceramic bodies out of them through a hydrothermal hot-pressing (HHP) method. Characteristic features of both the powder and ceramics were investigated by the X-ray diffraction method (XRD). Surface morphology of the ceramics was observed by scanning electron microscopy (SEM). Density, compressive strength and pore size distribution of the ceramics were measured. Crystalline structure of the newly developed OCP ceramics had no phase transformation from the starting materials. Moreover, the newly developed OCP ceramics had good mechanical properties only through the HHP treatment with a temperature as low as 110 degrees C. In order to evaluate bioactivity, the ceramics were immersed in simulating body fluid (SBF). It was predicted that OCP and Adi-OCP had better bioactivity than that of conventional HAp ceramics. (C) 2009 Elsevier B.V. All rights reserved.