Where would I be without ivermectin? Capturing the benefits of community-directed treatment with ivermectin in Africa
Where would I be without ivermectin? Capturing the benefits of community-directed treatment with ivermectin in Africa
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DOI：
10.1111/j.1365-3156.2011.02735.x
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发表时间：
2011-05-01
影响因子：
3.3
通讯作者：
Leak, Stephen
中科院分区：
文献类型：
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作者：
Okeibunor, Joseph C.;Amuyunzu-Nyamongo, Mary;Leak, Stephen
记录人们对服用伊维菌素的益处的看法，作为长期持续遵守伊维菌素治疗的重要预测因素，并确定伊维菌素治疗的感知益处的社会人口学相关性。方法在喀麦隆、刚果民主共和国、尼日利亚和乌干达进行多地点研究。对从家庭治疗记录中随机选择的1600人进行结构化问卷调查。使用深度访谈指南对社区领导人、社区定向药物分销商和卫生工作者进行了访谈，同时与社区成员进行了焦点小组讨论，以了解反映他们对伊维菌素社区定向治疗的益处的看法的因素。收集有盘尾丝虫病特殊经历者的病例史。结果84.7%的应答者认为伊维菌素治疗有许多益处。CDTI的社会效益包括提高工作能力、同伴接受度和入学率。其他个人利益包括自尊/自尊，选举政治职位和改善家庭关系。对健康的好处包括改善皮肤质地和减少疾病。影响服用伊维菌素益处认知的重要人口统计学因素包括婚姻状况（P = 0.012）、年龄（P = 0.029）和在盘尾丝虫病流行社区的居住时间（P < 0.001）。另一个因素是个体对盘尾丝虫病感染易感性的感知（P < 0.0001）。结论重点关注CDTI的益处可为激励社区遵守伊维菌素长期治疗提供基础。结果表明，获取受益人对CDTI的看法是制作卫生教育材料的一种资源，以增加伊维菌素在流行国家的可持续性分配的重要性。
To document peoples' perceptions of the benefits of taking ivermectin, as an important predictor of sustained compliance with long-term ivermectin treatment, and to identify the socio-demographic correlates of perceived benefits of ivermectin treatment.MethodsMultisite study in Cameroon, DRC, Nigeria and Uganda. A structured questionnaire was administered to 1600 persons randomly selected from household treatment records. Community leaders, community-directed drug distributors (CDDs) and health workers were interviewed using in-depth interview guides, while focus group discussions (FGDs) were held with community members to capture factors that reflected their perception of benefits of community-directed treatment with ivermectin (CDTI). Case histories of persons with special experiences with onchocerciasis were collected.ResultsIn this study, 84.7% of respondents indicated that ivermectin treatment has many benefits. The social benefits of CDTI included improved ability to work, peer acceptance and improved school attendance. Other individual benefits included self-respect/esteem, election to political office and improved relationship in the homes. The health benefits included improved skin texture and less ill health. Important demographic factors that influenced perception of the benefits of taking ivermectin, include marital status (P = 0.012), age (P = 0.029) and length of stay in onchocerciasis-endemic communities (P < 0.001). Another factor was individual perception of susceptibility to onchocerciasis infection (P < 0.0001).ConclusionA programmatic focus on the benefits of CDTI could provide a basis for motivating communities to comply with long-term treatment with ivermectin. The results illustrate the importance of capturing beneficiaries' perceptions towards CDTI as a resource for producing health education materials for increasing the sustainability ivermectin distribution in endemic countries.