A Meta-Analysis of Mentalizing Impairments in Adults With Schizophrenia and Autism Spectrum Disorder
A Meta-Analysis of Mentalizing Impairments in Adults With Schizophrenia and Autism Spectrum Disorder
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DOI：
10.1093/schbul/sbt048
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发表时间：
2014-05-01
影响因子：
6.6
通讯作者：
Strube, Michael
中科院分区：
文献类型：
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作者：
Chung, Yu Sun;Barch, Deanna;Strube, Michael
心理化在自闭症谱系障碍（ASD）和精神分裂症（SCZ）中主要通过认知语言（称为言语）或眼睛（称为视觉）的情感识别心理化任务进行了研究。每种类型的任务被认为是衡量心理化的不同方面。每种疾病的临床特征和发展过程的差异可以预测每种类型的任务上的精神化表现的不同模式。为了验证这一点，我们对37项研究进行了荟萃分析，这些研究评估了SCZ或ASD成年人的口头或视觉心理化。我们发现，两个临床组的言语和视觉心智化任务中的损伤的估计效应量在统计学上很大，并且处于相似的水平（总体Hedges' g = 0.73-1.05）。对于每一种障碍，SCZ的成年人表现出更大的障碍，在言语（整体对冲的g = 0.99）比视觉心理化任务（整体对冲的g = 0.73; Qbet = 3.45，p =. 06，df = 1）。ASD成年患者在语言和视觉任务上没有表现出不同程度的损伤（Qbet = 0.08，p = 0.001）。78，df = 1）。这些结果表明，这两个临床组共享，至少部分，一些共同的认知处理缺陷与心智障碍。
Mentalizing has been examined both in autism spectrum disorder (ASD) and schizophrenia (SCZ) primarily by either cognitive-linguistic (referred to as verbal) or emotion recognition from eyes (referred to as visual) mentalizing tasks. Each type of task is thought to measure different aspects of mentalizing. Differences in clinical features and developmental courses of each disorder may predict distinct patterns of mentalizing performance across disorders on each type of task. To test this, a meta-analysis was conducted using 37 studies that assessed mentalizing either verbally or visually in adults with SCZ or ASD. We found that the estimated effect sizes of impairments in verbal and visual mentalizing tasks for both clinical groups were statistically large and at a similar level (overall Hedges' g = 0.73-1.05). For each disorder, adults with SCZ showed a trend towards larger impairments on verbal (overall Hedges' g = 0.99) than on visual mentalizing task (overall Hedges' g = 0.73; Qbet = 3.45, p =. 06, df = 1). Adults with ASD did not show different levels of impairment on the verbal versus visual tasks (Qbet = 0.08, p =. 78, df = 1). These results suggest that both clinical groups share, at least in part, some common cognitive processing deficits associated with mentalizing impairments.