Cold Spells and the Risk of Hospitalization for Asthma: New York, USA 1991-2006
Cold Spells and the Risk of Hospitalization for Asthma: New York, USA 1991-2006
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DOI：
10.1007/s00408-014-9645-y
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发表时间：
2014-12-01
期刊：
影响因子：
5
通讯作者：
Lin, Shao
中科院分区：
文献类型：
--
作者：
Fitzgerald, Edward F.;Pantea, Cristian;Lin, Shao
在美国纽约州进行了一项研究，以调查长期的极冷温度是否与因哮喘住院的风险增加有关，该研究确定了1991年11月至2006年4月期间主要诊断为哮喘的住院病例。将连续三天或三天以上的感冒期定义为入院前一周内的每日平均普遍表观温度（UAT）在第10百分位数或更低。使用时间序列分析将感冒期期间和之后哮喘住院的百分比变化与感冒期前的平均每日住院人数进行比较。冬季感冒期期间的平均温度（12月至3月）为-15 A摄氏度，而11月和4月的寒冷天气分别为-6和-2 A摄氏度。冬季寒冷期与全州哮喘入院率平均下降4.9%相关（95%CI-7.8，-1.9%）。在寒冷天气后，在冬季的几个月里，没有统计学上的显著变化，但在11月的过渡月份，哮喘住院率在寒冷天气后增加（平均值= 9.6，95% CI 5.5，13.9%）和4月（平均值= 5.0，95%CI 1.2，9.0%）。结果表明，在长时间的严重寒冷期间，哮喘患者可以遵守医疗指南并限制他们的暴露，从而防止恶化。在11月和4月这两个较为温和的月份，他们可能不太可能改变自己的行为。
A study was conducted to investigate whether prolonged periods of very cold temperatures were associated with an increased risk of hospitalization for asthma.Hospitalization admissions with a principal diagnosis of asthma were identified in New York State, USA, for the months November through April from 1991 to 2006. A cold spell was defined as three or more consecutive days where the daily mean of universal apparent temperature (UAT) within a week prior to admission was at the 10th percentile or less. The percentage change in asthma hospitalizations during and after a cold spell was compared to the average daily number of hospitalizations preceding the cold spell using time series analysis.The average temperature during winter cold spells (December through March) was -15 A degrees C, compared to -6 and -2 A degrees C for cold spells in November and April, respectively. Cold spells during the winter months were associated with a mean decline of 4.9 % in asthma admissions statewide (95 % CI -7.8, -1.9 %). After a cold spell, no statistically significant changes were apparent during the winter months, but asthma hospitalizations increased after cold spells in the transitional months of November (mean = 9.6, 95 % CI 5.5, 13.9 %) and April (mean = 5.0, 95 % CI 1.2, 9.0 %).The results suggest that during prolonged periods of severe cold asthmatics may adhere to medical guidelines and limit their exposure, thereby preventing exacerbations. They may be less likely to alter their behavior in the more moderate months of November and April.