PROPAGATION VELOCITY AND REFLECTION OF PRESSURE WAVES IN THE CANINE CORONARY-ARTERY
PROPAGATION VELOCITY AND REFLECTION OF PRESSURE WAVES IN THE CANINE CORONARY-ARTERY
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DOI：
10.1152/ajpheart.1979.237.4.h469
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发表时间：
1979-01-01
影响因子：
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通讯作者：
RENEMAN, RS
中科院分区：
文献类型：
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作者：
ARTS, T;KRUGER, RTI;RENEMAN, RS
通过确定沿该动脉的压力脉冲之间的延迟时间来测量狗的左冠状动脉前降支（LADC）中的压力波速度。仅当压力测量部位远端的压力波反射不明显时才可以应用该方法。从冠状动脉的 Araldite 铸件中，发现了分叉近端 (dprox) 和远端 (ddist 1, ddist 2) 直径之间的以下关系：.**图形**。 = .**图形**。 + .**图形**。表明分叉处的反射最小。在狗中，通过在舒张期诱导主动脉中的压力脉冲并测量冠状动脉外周阻力的不同水平的LADC的近端和远端的压力和体积流量来研究反射。高频分量（> 7 Hz）的反射微不足道，允许应用对低频反射不敏感的波前速度测量方法。在 LADC 中的压力为 13.3 kPa 时，该速度为 8.6 +/-。 1.4 m/s（平均值.+-.SD）。计算出的LADC的动态横截面刚度(ΔP/(ΔA/A))为97±。动脉压为 13.3 kPa 时为 11 kPa（平均±SE）。
The pressure wave velocity in the anterior descending branch of the left coronary artery (LADC) of the dog was measured by determining the delay time between pressure pulses along this artery. This method can only be applied if reflections of the pressure wave distal to the sites of pressure measurement are insignificant. From araldite casts of the coronary arteries the following relation between the diameter proximal to (dprox) and distal to (ddist 1, ddist 2) a bifurcation was found: .**GRAPHIC**. = .**GRAPHIC**. + .**GRAPHIC**. indicating that reflections at a bifurcation are minimal. In dogs reflections were studied by inducing during diastole a pressure pulse in the aorta and measuring pressure and volume flow proximal to and pressure distal to a segment of the LADC at various levels of the coronary peripheral resistance. Reflection of high-frequency components (> 7 Hz) was insignificant, allowing application of the method for measuring the wave-front velocity, which is insensitive to low-frequency reflection. At a pressure in the LADC of 13.3 kPa this velocity was 8.6 .+-. 1.4 m/s (mean .+-. SD). The calculated dynamic cross-sectional stiffness (.DELTA.P/(.DELTA.A/A)) of the LADC was 97 .+-. 11 kPa (mean .+-. SE) at an arterial pressure of 13.3 kPa.