Europium-based aminoclay containing carbon dots: A new visual fluorescence platform for visual point-of-care testing of tetracycline in various real samples
Europium-based aminoclay containing carbon dots: A new visual fluorescence platform for visual point-of-care testing of tetracycline in various real samples
复制标题
含碳点的铕基氨基粘土：一种新的视觉荧光平台，用于各种真实样品中四环素的视觉即时检测
DOI：
10.1016/j.jlumin.2021.118497
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发表时间：
2022
影响因子：
3.6
通讯作者：
Zhao Tongqian
中科院分区：
文献类型：
--
作者：
Jia Lei;Chen Xiangzhen;Xu Jun;Zhang Lina;Dong Xiyan;Zhao Dan;Bi Ning;Zhu Taofeng;Zhao Tongqian
实现四环素的实时准确检测具有重要意义。本研究通过后续的表面修饰，引入对四环素具有良好灵敏度的碳量子点铕基氨基粘土，实现四环素的比值荧光检测。随着四环素浓度的增加，稀土铕荧光团的荧光强度不断增强，而CD的荧光强度基本不变。CIE色品坐标证实了探头的发光颜色可以从蓝色到红色连续调节。结果表明，该方法对TC在0 ~ 12.5 μM和10-25 μM范围内具有良好的线性关系，灵敏度高，检出限为3.133 nM。快速监测时间短至30 s，完全满足现场检测的要求。该荧光检测策略在各种实际样品中TC的现场检测中是可靠可行的。此外，设计了一种基于垂直浮子结构的TC漂浮检测仪，实现了模拟流动环境下TC的快速可视化检测。传感平台的优越性为TC残留的即时监测开辟了新途径。
It is of vital significance to achieve accurate real-time detection of tetracycline (TC). In this research, the ratio fluorescence detection of tetracycline is realized by introducing europium-based aminoclay containing carbon dots with good sensitivity to tetracycline through subsequent surface modification. With the increase of tetracycline concentration, the fluorescence intensity of rare earth europium fluorophore increases continuously, while the fluorescence intensity of CDs is basically unchanged. The CIE chromaticity coordinate confirms that the luminous color of the probe can be adjusted continuously from blue to red. The results exhibit this approach owns the favourable linearity to TC within 0–12.5 μM and 10–25 μM, and the high sensitivity with a low detection limit of 3.133 nM. Moreover, it can entirely satisfy the requirements of field detection because the rapid monitoring time as short as 30 s. The multicolor fluorescence detection strategy is reliable and feasible in the field test of TC in various actual samples. In addition, a TC floating detector based on vertical float structure is designed to achieve the rapid visual detection of TC in simulated flow environment. The superiority of the sensing platform opens up a neo-pathway for point-of-care monitoring of TC residues.