PTC/PROP TASTING - ANATOMY, PSYCHOPHYSICS, AND SEX EFFECTS
PTC/PROP TASTING - ANATOMY, PSYCHOPHYSICS, AND SEX EFFECTS
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DOI：
10.1016/0031-9384(94)90361-1
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发表时间：
1994-12-01
影响因子：
2.9
通讯作者：
MILLER, IJ
中科院分区：
文献类型：
--
作者：
BARTOSHUK, LM;DUFFY, VB;MILLER, IJ
由于对苯硫脲（PTC）及其化学相对物6-正丙基硫氧嘧啶（PROP）的味觉盲视，人类的味觉世界各不相同。我们回顾了早期的PTC研究，并应用现代统计分析表明，更高频率的妇女品尝PTC晶体，品尝（阈值分类）。在我们的实验室中，PROP苦味的缩放导致鉴定出将PROP评定为强烈苦味的味觉者（超味觉者）的子集。超味觉者还从各种苦味和甜味物质中感知到更强烈的味道，并且从口腔刺激物（酒精和辣椒素）中感知到更多的灼伤。舌前部味觉感受器（菌状乳头、味蕾）的密度与PROP的感知苦味显著相关，并支持超级味觉者的概念。我们实验室的心理物理学研究数据也显示了性别效应;女性更容易成为超级味觉者。解剖学数据也支持性别差异;女性有更多的菌状乳头和更多的味蕾。PTC/PROP品尝和食物行为的未来调查应包括规模确定supertasters和单独的性别影响。
Taste worlds of humans vary because of taste blindness to phenylthiocarbamide (PTC) and its chemical relative, 6-n-propylthiouracil (PROP). We review early PTC studies and apply modern statistical analyses to show that a higher frequency of women tasted PTC crystals, and were tasters (threshold classification). In our laboratory, scaling of PROP bitterness led to the identification of a subset of tasters (supertasters) who rate PROP as intensely bitter Supertasters also perceive stronger tastes from a variety of bitter and sweet substances, and perceive more burn from oral irritants (alcohol and capsaicin). The density of taste receptors on the anterior tongue (fungiform papillae, taste buds) correlate significantly with perceived bitterness of PROP and support the supertaster concept. Psychophysical data from studies in our laboratory also show a sex effect; women are supertasters more frequently. The anatomical data also support the sex difference; women have more fungiform papillae and more taste buds. Future investigations of PTC/PROP tasting and food behaviors should include scaling identify supertasters and separate sex effects.