The Application of Bio-orthogonality for In Vivo Animal Imaging.
The Application of Bio-orthogonality for In Vivo Animal Imaging.
复制标题
生物实行性在体内动物成像中的应用。
DOI：
10.1021/cbmi.3c00033
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发表时间：
2023-08-28
期刊：
影响因子：
--
通讯作者：
Ran, Chongzhao
中科院分区：
文献类型：
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作者：
Yang, Jun;Zhu, Biyue;Ran, Chongzhao
近年来，生物正交性的应用极大地促进了生物学研究的许多方面。特别是，生物正交化学已经改变了生物研究，包括体外共轭化学，目标识别和生物医学成像。在这篇综述中，我们强调了近年来发表的生物正交体内成像的例子。我们将参考文献分为两大类：生物正交化学相关成像和生物正交非共轭配对的体内成像。最后，我们讨论了生物正交性在体内成像中的挑战和机遇。
The application of bio-orthogonality has greatly facilitated numerous aspects of biological studies in recent years. In particular, bio-orthogonal chemistry has transformed biological research, including in vitro conjugate chemistry, target identification, and biomedical imaging. In this review, we highlighted examples of bio-orthogonal in vivo imaging published in recent years. We grouped the references into two major categories: bio-orthogonal chemistry-related imaging and in vivo imaging with bio-orthogonal nonconjugated pairing. Lastly, we discussed the challenges and opportunities of bio-orthogonality for in vivo imaging.