DIARRHEA CAUSED BY SHIGELLA, ROTAVIRUS, AND GIARDIA IN DAY-CARE-CENTERS - PROSPECTIVE-STUDY
DIARRHEA CAUSED BY SHIGELLA, ROTAVIRUS, AND GIARDIA IN DAY-CARE-CENTERS - PROSPECTIVE-STUDY
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DOI：
10.1016/s0022-3476(81)80956-0
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发表时间：
1981-01-01
影响因子：
5.1
通讯作者：
EVANS, DJ
中科院分区：
文献类型：
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作者：
PICKERING, LK;EVANS, DG;EVANS, DJ
19个小时。对20个日托中心的儿童进行了前瞻性研究，以确定儿童、工作人员和家庭成员中胃肠炎的发生、原因和传播。9个中心有15起腹泻暴发，涉及195人。在所有暴发中都发现了一种肠道病原体。在5起暴发疫情中检出志贺氏菌，2起轮状病毒，1起贾第鞭毛虫，其余7起发现多种肠道病原体。轮状病毒和贾第鞭毛虫只发生在3岁的儿童中；志贺氏菌病发生在所有年龄段。在6个疾病预防控制中心中，68例单一腹泻病例与暴发无关；仅在3人(4%)中发现肠道病原体。家庭成员(34)，(11%)在6个DCC中发生与胃肠炎相关的腹泻，评估这一问题。根据在DCC暴发中发现的微生物，家庭中腹泻的二次发病率为：志贺氏菌，26%；轮状病毒，15%；兰布里亚革兰氏菌，17%。因此，DCC可能在美国胃肠炎的流行病学和传播中发挥重要作用。
A 19 mo. prospective study of children attending 20 day care centers [DCC] was conducted to determine the occurrence, causes and transmission of gastroenteritis among children, staff and family members. Nine centers had 15 outbreaks of diarrhea involving 195 persons. An enteropathogen was identified in all outbreaks. Shigella was detected in 5 outbreaks, rotavirus in 2, Giardia in 1, and, in the remaining 7, multiple enteropathogens were identified. Rotavirus and Giardia occurred only in children < 3 yr of age; shigellosis occurred at all ages. IN 6 DCC, 68 single cases of diarrhea were not associated with an outbreak; an enteropathogen was identified in only 3 (4%) persons. Family members (34), (11%) developed diarrhea associated with the occurrence of gastroenteritis in children in 6 DCC evaluated for this problem. Secondary attack rates of diarrhea in families according to organisms identified in the DCC outbreaks were: Shigella, 26%; rotavirus, 15%; and G. lamblia, 17%. Thus, DCC may play an important role in the epidemiology and transmission of gastroenteritis in the USA.