Two Cases of Cerebral Infarction due to Focal Irradiation for Glioma in Adults
Two Cases of Cerebral Infarction due to Focal Irradiation for Glioma in Adults
复制标题
成人胶质瘤局部照射致脑梗塞二例
DOI：
10.11477/mf.1436203018
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发表时间：
2015
期刊：
影响因子：
--
通讯作者：
Kohmura E.
中科院分区：
文献类型：
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作者：
Minami N;Mizukawa K;Iwahashi H;Nagashima H;Tanaka K;Sasayama T;Hosoda K;Mukumoto N;Sasaki R;Kohmura E.
放射性血管病变是放射治疗的一种并发症。大多数关于颅内肿瘤的照射后缺血性卒中的报告仅限于儿科病例。在此我们报告两个成人病例，由于大脑前中动脉狭窄或闭塞而引起迟发性脑梗塞，似乎是由于恶性胶质瘤的局部放射治疗所致。虽然放射性诱发的缺血性卒中在成人中相对少见，但由于治疗的进步，恶性胶质瘤患者放射性诱发的卒中的发病率可能会随着生存期的延长而增加。因此，放射治疗后定期评估颅内血管是必要的。
Radiation-induced vasculopathy is a complication of radiation therapy. Most reports regarding post-irradiation ischemic stroke with intracranial tumors are restricted to pediatric cases. Here we report two adult cases of delayed brain infarction due to anterior and middle cerebral artery stenosis or occlusion seemingly caused by focal radiation therapy for malignant glioma. Although radiation-induced ischemic stroke in adults is relatively uncommon, it is possible that the morbidity rate of radiation-induced stroke in malignant glioma patients will increase with prolonged survival due to advances in therapy. Therefore, regular evaluation of intracranial vasculature following radiation therapy is necessary.