SPECTROSCOPIC INVESTIGATION OF SWAINSONINE - ALPHA-MANNOSIDASE INHIBITOR ISOLATED FROM SWAINSONA-CANESCENS
SPECTROSCOPIC INVESTIGATION OF SWAINSONINE - ALPHA-MANNOSIDASE INHIBITOR ISOLATED FROM SWAINSONA-CANESCENS
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DOI：
10.1071/ch9792257
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发表时间：
1979-01-01
影响因子：
1.1
通讯作者：
HUXTABLE, CR
中科院分区：
文献类型：
--
作者：
COLEGATE, SM;DORLING, PR;HUXTABLE, CR
从燕尾草中分离到一种有效的α-甘露糖苷酶抑制剂。光谱分析表明该缓蚀剂为中氮三醇，其相对立体化学为8a-β-中氮三醇-Lα，2-α，8-β-三醇。
A potent inhibitor of α-mannosidase was isolated from Swainsona canescens. The inhibitor was shown to be an indolizidinetriol by spectroscopic techniques and the relative stereochemistry was defined as 8aβ-indolizidine-lα,2α,8β-triol.