Balance Dysfunction in Parkinson's Disease: The Role of Posturography in Developing a Rehabilitation Program.
Balance Dysfunction in Parkinson's Disease: The Role of Posturography in Developing a Rehabilitation Program.
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DOI：
10.1155/2015/520128
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发表时间：
2015
期刊：
影响因子：
--
通讯作者：
Frazzitta G
中科院分区：
文献类型：
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作者：
Ferrazzoli D;Fasano A;Maestri R;Bera R;Palamara G;Ghilardi MF;Pezzoli G;Frazzitta G
帕金森氏病（PD）的平衡功能障碍（BD）是一种致残性症状，难以治疗，易诱发福尔斯。多巴胺能药物或深部脑刺激并不总是提供BD的显着改善，康复方法也未能恢复这种状况。在这项研究中，我们调查了定量姿势图指标的适用性，以早期识别患者可能发展为致残性BD。没有主诉主观BD的帕金森病患者和对照组使用姿势描记平台（PP）进行测试，睁眼（OE）并执行简单的认知任务[计数（OEC）]。我们发现，患者在OE条件下显示较高的总标准差（SD）的身体摇摆和沿着内侧（ML）轴。此外，在贝格平衡量表正常的一个亚组中，OE条件下身体摇摆的总SD和ML SD以及OEC下身体摇摆的总SD也高于对照组。我们的结论是，BD帕金森病患者可以发现其外观之前使用PP和这些数据可能允许开发特定的康复治疗，以防止或延迟其发病。
Balance dysfunction (BD) in Parkinson's disease (PD) is a disabling symptom, difficult to treat and predisposing to falls. The dopaminergic drugs or deep brain stimulation does not always provide significant improvements of BD and rehabilitative approaches have also failed to restore this condition. In this study, we investigated the suitability of quantitative posturographic indicators to early identify patients that could develop disabling BD. Parkinsonian patients not complaining of a subjective BD and controls were tested using a posturographic platform (PP) with open eyes (OE) and performing a simple cognitive task [counting (OEC)]. We found that patients show higher values of total standard deviation (SD) of body sway and along the medio-lateral (ML) axis during OE condition. Furthermore, total and ML SD of body sway during OE condition and total SD of body sway with OEC were higher than controls also in a subgroup of patients with normal Berg Balance Scale. We conclude that BD in Parkinsonian patients can be discovered before its appearance using a PP and that these data may allow developing specific rehabilitative treatment to prevent or delay their onset.