The sepsis six and the severe sepsis resuscitation bundle: a prospective observational cohort study
The sepsis six and the severe sepsis resuscitation bundle: a prospective observational cohort study
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DOI：
10.1136/emj.2010.095067
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发表时间：
2011-06-01
影响因子：
3.1
通讯作者：
Galvin, Clare
中科院分区：
文献类型：
--
作者：
Daniels, Ron;Nutbeam, Tim;Galvin, Clare
背景在英国，严重的脓毒症每年可能导致约37000人死亡。在国际存活脓毒症运动(SSC)护理包发布五年后，只有不到七分之一的患者达到了严重脓毒症患者的护理标准。方法这是一项跨越500张床位的急性综合医院的前瞻性观察队列研究，以评估两种干预措施的交付和影响：SSC复苏包和旨在促进分娩的新干预措施--败血症6。过程测量包括依从性和败血症6；结果测量是出院时的死亡率。结果567名患者的数据适合分析。与基准相比，对捆绑包的遵从性有所提高。在接受脓毒症6号治疗的患者(n=220)中，84.6%的患者实现了复苏，而其他患者的比例仅为5.8%。干预措施的实施与死亡率的降低有关：对于脓毒症6(n=220)，20.0%与44.1%(P
Background Severe sepsis is likely to account for around 37 000 deaths annually in the UK. Five years after the international Surviving Sepsis Campaign (SSC) care bundles were published, care standards in the management of patients with severe sepsis are achieved in fewer than one in seven patients.Methods This was a prospective observational cohort study across a 500-bed acute general hospital, to assess the delivery and impact of two interventions: the SSC resuscitation bundle and a new intervention designed to facilitate delivery, the sepsis six. Process measures included compliance with the bundle and the sepsis six; the outcome measure was mortality at hospital discharge.Results Data from 567 patients were suitable for analysis. Compliance with the bundle increased from baseline. 84.6% of those receiving the sepsis six (n=220) achieved the resuscitation bundle compared with only 5.8% of others. Delivery of the interventions had an association with reduced mortality: for the sepsis six (n=220), 20.0% compared with 44.1% (p