The neural basis of loss aversion in decision-making under risk
The neural basis of loss aversion in decision-making under risk
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DOI：
10.1126/science.1134239
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发表时间：
2007-01-26
期刊：
影响因子：
56.9
通讯作者：
Poldrack, Russell A.
中科院分区：
文献类型：
--
作者：
Tom, Sabrina M.;Fox, Craig R.;Poldrack, Russell A.
在做出决策时，人们通常对损失比对同等收益表现出更大的敏感性。我们研究了当个体决定是否接受或拒绝提供50/50赚钱或赔钱机会的赌博时，损失厌恶的神经相关性。随着潜在收益的增加，一系列广泛的区域（包括中脑多巴胺能区域及其靶点）显示出增加的活性。潜在的损失表现在几个同样对收益敏感的领域的活动减少。最后，行为损失厌恶的个体差异预测的神经损失厌恶在几个地区，包括腹侧纹状体和前额叶皮层的措施。
People typically exhibit greater sensitivity to losses than to equivalent gains when making decisions. We investigated neural correlates of loss aversion while individuals decided whether to accept or reject gambles that offered a 50/50 chance of gaining or losing money. A broad set of areas ( including midbrain dopaminergic regions and their targets) showed increasing activity as potential gains increased. Potential losses were represented by decreasing activity in several of these same gain-sensitive areas. Finally, individual differences in behavioral loss aversion were predicted by a measure of neural loss aversion in several regions, including the ventral striatum and prefrontal cortex.