Associations of dual sensory impairment with incident mobility and ADL difficulty.
Associations of dual sensory impairment with incident mobility and ADL difficulty.
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DOI：
10.1111/jgs.17764
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发表时间：
2022-07
影响因子：
6.3
通讯作者：
Jones, Richard N.
中科院分区：
文献类型：
--
作者：
Armstrong, Nicole M.;Teixeira, Camila Vieira Ligo;Gendron, Colby;Brenowitz, Willa D.;Lin, Frank R.;Swenor, Bonnelin;Deal, Jennifer A.;Simonsick, Eleanor M.;Jones, Richard N.
缺乏研究客观测量的双重感觉障碍（DSI）与事件的移动性和日常生活活动（ADL）的困难纵向的关联。考克斯比例风险模型被用来检验DSI和单一感觉障碍的关系（听力、视力）伴有偶发性行动困难（许多问题或无法行走1/4英里和/或爬10步）和ADL困难长达6年的随访，在健康，衰老和身体成分研究的2,020名参与者中进行，该研究是匹兹堡70-79岁的老年人队列，宾夕法尼亚州和田纳西州的孟菲斯。视力损害（VI）定义为视力受损（Bailey-Lovie距离测试为20/50或更差）和对比敏感度受损（Pelli-Robson测试为<1.3 log单位），听力损害（HI）定义为听力较好的耳朵中纯音平均值>25分贝。模型根据年龄、种族、性别、教育、糖尿病、抑郁症状、高血压、20米步行的步态速度、总体认知评分、流行心血管疾病和体重指数进行调整。有23%的患者患有DSI（n=459）。DSI与活动性（风险比[HR]=2.25，95%置信区间[CI]：1.47，3.43）和ADL困难（HR=2.26，95% CI：1.50，3.40）事件报告的风险增加相关。单独的VI或HI均与任一结局的风险无关。DSI与事件移动性和ADL困难的风险增加相关。DSI患者的康复和适应性环境变化对最大限度地提高活动能力和日常功能可能很重要。
There is a dearth of studies examining the associations of objectively measured dual sensory impairment (DSI) with incident mobility and activities of daily life (ADL) difficulty longitudinally. Cox proportional hazards models were used to examine the associations of DSI and single sensory impairment (hearing, vision) with incident mobility difficulty (many problems or inability to walk ¼ mile and/or climb 10 steps) and ADL difficulty up to six years of follow-up among 2,020 participants of the Health, Aging and Body Composition Study, a cohort of older adults aged 70–79 years from Pittsburgh, PA and Memphis, TN. Vision impairment (VI) was defined as impaired visual acuity (20/50 or worse on Bailey-Lovie distance test) and contrast sensitivity (<1.3 log units on Pelli-Robson test), and hearing impairment (HI) was defined as pure-tone average in better-hearing ear >25 decibels. Models were adjusted by age, race, sex, education, diabetes, depressive symptoms, hypertension, gait speed from 20-meter walk, global cognition score, prevalent cardiovascular disease, and body mass index. There were 23% with DSI (n=459). DSI was associated with increased risk of both incident report of mobility (Hazard Ratio [HR]=2.25, 95% Confidence Interval [CI]: 1.47, 3.43) and ADL difficulty (HR=2.26, 95% CI: 1.50, 3.40). Neither VI nor HI alone were associated with risk of either outcome. DSI is associated with increased risk of incident mobility and ADL difficulty. Rehabilitation and adaptive environmental changes for individuals living with DSI may be important to maximize mobility and daily function.
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DOI：
10.1056/nejmra1616601
发表时间：
2017-12-21
期刊：
The New England journal of medicine
影响因子：
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影响因子：
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发表时间：
2020-03-01
影响因子：
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