Vulnerability to ventricular arrhythmia: assessment by mapping of body surface potential.
Vulnerability to ventricular arrhythmia: assessment by mapping of body surface potential.
复制标题
室性心律失常的脆弱性：通过体表电位测绘进行评估。
DOI：
10.1161/01.cir.73.4.684
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发表时间：
1986
期刊：
影响因子：
37.8
通讯作者：
E. Smith
中科院分区：
文献类型：
--
作者：
M. Gardner;T. Montague;C. Armstrong;B. Horáček;E. Smith
现在已经确定，心室心肌对重复性心律失常的易感性在局部恢复时间大于正常差异的情况下增加。局部恢复在心电图波形中反映为心室偏转面积（QRST时间积分），因此不同的心室恢复可能表现在该质量的体表分布上。为了评估这种可能性，我们同时获得了140名受试者（8至75岁）前后躯干的120导联心电图，分组如下：A组，97名正常受试者；B组16例室性颤动或持续性室性心动过速复苏；C组27例心肌梗死后6 ~ 12个月无明显心律失常的患者。在每个受试者中，评估每个导联的QRST积分并绘制等积分等高线图。根据极值的数量给每张地图打分；每个最大值或最小值都得1分，除了右肩同时发生的前后最小值（经常发生在正常受试者中），它们加在一起只得1分。除A组1名受试者外，其余受试者均有双极QRST积分图（平均+/- SD评分2.11 +/- 0.2）。相反，B组16例患者中有10例（62.5%）得分在3分及以上（平均3.16±1.08;p < 0.05）。01组vs A组)。C组患者为中等值，27例患者中有8例（29.6%）得分为3分或以上（平均2.46 +/- 83）；与B组相比，p <。p <。（摘要截短于250字）
It is now well established that the vulnerability of the ventricular myocardium to repetitive dysrhythm increases in the presence of greater than normal disparity local recovery times. Local recovery is reflected in the electrocardiographic waveform as an area of the ventricular deflection (QRST time integral), and thus disparate ventricular recovery may be manifested in the body surface distribution of this quality. To assess this possibility, we obtained simultaneous 120-lead electrocardiograms from both the anterior and posterior torso in 140 subjects (ages 8 to 75) grouped as follows: group A, 97 normal subjects; group B, 16 patients resuscitated from ventricular fibrillation or sustained ventricular tachycardia; and group C, 27 patients 6 to 12 months after myocardial infarction but without clinically significant arrhythmia. In each subject, the QRST integral was evaluated for each lead and isointegral contour maps were plotted. A score was assigned to each map, based on the number of extrema; each maximum or minimum scored one point, with the exception of simultaneously occurring anterior and posterior minima on the right shoulder (frequently occurring in normal subjects), which scored together only one point. All but one group A subject had dipolar QRST integral maps (mean +/- SD score 2.11 +/- 0.2). Conversely, 10 of 16 (62.5%) group B patients had scores of 3 or more (mean 3.16 +/- 1.08; p less than .01 vs group A). Group C patients had intermediate values, with eight of 27 (29.6%) scoring 3 or more (mean 2.46 +/- 83); this was less than in group B (p less than .01), but more (p less than .05) than in group A.(ABSTRACT TRUNCATED AT 250 WORDS)