Some new aspects of the pathology, pathogenesis, and aetiology of disseminated lung lesions in slaughter pigs
Some new aspects of the pathology, pathogenesis, and aetiology of disseminated lung lesions in slaughter pigs
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DOI：
10.1034/j.1600-0463.2003.1110501.x
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发表时间：
2003-05-01
期刊：
影响因子：
2.8
通讯作者：
Jensen, HE
中科院分区：
文献类型：
--
作者：
Liljegren, CH;Aalbæk, B;Jensen, HE
屠宰时因明显存在脓毒性肺病变（定义为含有脓和/或坏死物质的播散性病变）而拒绝供人食用的40头猪，对肺、脾、肝和肾进行了扩展的肉眼检查。从每只动物中采集几处肺部病变样本进行组织学和细菌学检查。还对肾脏和脾脏样本进行了细菌学检查。在大体水平上，确定了四组肺部病变：1）具有脓和/或坏死物质内容物的播散性病灶（n=26）; 2）具有纤维增生中心区域的播散性或多灶性瘀斑（n=9）; 3）非肺炎性病变，即，弥散性肺不张区域（n=1）或屠宰过程中出现的出血区域（n=1）;和4）无弥散性分布模式的化脓性病变（n=3）。在组织学上，播散性化脓/坏死病灶被确定为：A）脓肿（n=10）; B）坏死性病变（n=6）;和Q扩张或扩张样细支气管伴脓液和坏死物质（n=10）。组织病理学证实了肉眼观察到的弥散性纤维增生中心伴周围瘀斑（n=9）。5头猪的肝脏含有与猪蛔虫幼虫迁移相关的多个慢性间质纤维化区域（“乳斑肝”）。肝内病变的发生率明显高于肝内病变（p
From 40 pigs rejected for human consumption at slaughter due to an apparent presence of pyemic lung lesions (defined as disseminated processes containing pus and/or necrotic material), the lungs, spleen, liver, and kidneys were subjected to an extended macroscopic examination. Several lung lesions were sampled from each animal for histological and bacteriological examination. Samples from the kidneys and spleens were also subjected to bacteriological examination. At gross level, four groups of lung lesions were identified: 1) disseminated foci with contents of pus and/or necrotic material (n=26); 2) disseminated or multifocally located ecchymoses with a central area of fibroplasia (n=9); 3) non-pneumonic lesions, i.e., disseminated areas of atelectasis (n=1) or haemorrhagic areas developing due to the process of slaughter (n=1); and 4) suppurative lesions without a disseminated distribution pattern (n=3). Histologically, the disseminated suppurative/necrotic foci were identified as: A) abscesses (n=10); B) necrotic lesions (n=6); and Q ectatic or ectatic-like bronchioles with contents of pus and necrotic material (n=10). The macroscopic observation of disseminated centres of fibroplasia with peripheral ecchymoses (n=9) was confirmed histopathologically. The livers of five pigs contained multiple areas of chronic interstitial fibrosis related to migration of Ascaris suum larvae ("milk spotted liver"). Such hepatic lesions were significantly (p