Chronic pain in a large community sample of persons with multiple sclerosis
Chronic pain in a large community sample of persons with multiple sclerosis
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DOI：
10.1191/1352458503ms939oa
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发表时间：
2003-01-01
影响因子：
5.8
通讯作者：
Kraft, GH
中科院分区：
文献类型：
--
作者：
Ehde, DM;Gibbons, LE;Kraft, GH
简介：本研究在一个大的以社区为基础的多发性硬化症（MS）患者样本中检查了疼痛的患病率、强度、干扰和生物心理社会相关性。方法：邮件调查返回442名成员的国王县（WA）MS协会。评估平均疼痛强度、疼痛相关活动干扰、抑郁症状和MS严重程度。结果：44%的人在完成调查前的三个月内报告了持续的，令人烦恼的疼痛。疼痛的参与者在0（无疼痛）至10（疼痛最严重）量表上报告的平均疼痛强度评分为5.2（SD=2.3）。27%的人报告了严重的疼痛（评分为7-10），而51%的疼痛患者认为疼痛对日常活动的干扰为零到最小。20%的人报告说，由于疼痛，他们的活动受到严重干扰。在多变量模型中，MS疾病的严重程度，婚姻状况和自我评价的整体健康状况与疼痛相关的干扰活动显着相关。结论：大约四分之一的样本描述了慢性疼痛问题，其特征是严重的疼痛强度和显着的疼痛相关的活动干扰。疼痛导致的残疾可能比以前认识到的MS人群更重要。
Introduction: This study examined the prevalence, intensity, interference, and biopsychosocial correlates of pain in a large community-based sample of persons with multiple sclerosis (MS). Methods: Mail surveys were returned by 442 members of the King County (WA) MS Association. Average pain intensity, pain-related activity interference, depressive symptoms and severity of MS were assessed. Results: Forty-four percent reported persistent, bothersome pain in the three months prior to completing the survey. Participants with pain reported an average pain intensity rating of 5.2 (SD=2.3) on the 0 (no pain) to 10 (pain as bad as could be) scale. Twenty-seven percent reported severe pain (score of 7-10), while 51% of those with pain rated the interference of their pain with daily activities as none to minimal. Twenty percent reported severe interference in activities as a result of pain. In multivariate modeling, MS illness severity, marital status, and self-ratings of overall health were significantly associated with pain-related interference with activities. Conclusions: Approximately a fourth of this sample described having a chronic pain problem characterized by severe pain intensity and significant pain-related interference with activities. Disability due to pain may be more important than previously recognized for the MS population.