Comparison of acute phase reaction and postoperative stress in pigs undergoing video-assisted thoracoscopic versus thoracotomy pneumonectomy.
Comparison of acute phase reaction and postoperative stress in pigs undergoing video-assisted thoracoscopic versus thoracotomy pneumonectomy.
复制标题
电视胸腔镜与开胸肺切除术猪急性期反应和术后应激的比较
DOI：
10.1186/s13028-016-0256-x
复制
发表时间：
2016-11-09
影响因子：
2.1
通讯作者：
Wang HB
中科院分区：
文献类型：
--
作者：
Liu HF;Gao L;Liu T;Yan-Jiang;Wang HB
Video-assisted thoracoscopic surgery (VATS) has been used for many thoracic diseases as an alternate approach to thoracotomy. The aim of this study was to compare the surgical outcome of pneumonectomy using VATS with that using thoracotomy pneumonectomy in pigs. Fourteen pigs were equally divided into two groups; one group underwent VATS and the other group underwent transthoracic pneumonectomy. We monitored pre-, intra-, and post-operative physiologic parameters, along with blood cell count, serum C-reactive protein (CRP), serum amyloid A (SAA), interleukin-6 (IL-6) and cortisol. The differences between the two approaches were analyzed. Mean surgical time in the VATS group (160.6 ± 16.2 min) was significantly longer than that in the thoracotomy group (123.7 ± 13.2 min). In both groups, CRP and IL-6 concentrations were significantly increased at postoperative 4 h, and then gradually decreased to preoperative levels. CRP and IL-6 at postoperative day 1 were significant lower in the VATS group compared with the thoracotomy group. SAA was significantly increased at postoperative days 1 and 3 in both groups compared with preoperative levels. Cortisol was significantly increased immediately after surgery in both groups compared with preoperative levels, and was significantly higher in the thoracotomy group than the VATS group at postoperative 4 h and 1 day. There was no difference between the two groups in physiologic parameters and blood cell count. However, the results indicate that VATS resulted in a smaller incision, less acute-phase reaction, less stress and less pain compared with thoracotomy pneumonectomy.
登录
查看更多内容
影响因子：
1.8
作者：
Bleakley, Seth;Duncan, Colleen G.;Monnet, Eric
通讯作者：
Monnet, Eric
影响因子：
4.6
作者：
KIRBY, TJ;RICE, TW
通讯作者：
RICE, TW
影响因子：
4.6
作者：
Luckraz, Heyman;Rammohan, Kandadai S.;O'Keefe, Peter A.
通讯作者：
O'Keefe, Peter A.
影响因子：
3.4
作者：
Falcoz, Pierre-Emmanuel;Puyraveau, Marc;Brunelli, Alessandro
通讯作者：
Brunelli, Alessandro
影响因子：
2.2
作者：
Bufalari, Antonello;De Monte, Valentina;Vannucci, Jacopo
通讯作者：
Vannucci, Jacopo