Polymorphic Anhydrous Cocrystals of Gallic Acid and Acetamide from Methanol: Pointers toward a Stable Cocrystal Form

Polymorphic Anhydrous Cocrystals of Gallic Acid and Acetamide from Methanol: Pointers toward a Stable Cocrystal Form
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DOI:
10.1021/cg300536n
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发表时间:
2012-06-01
影响因子:
3.8
通讯作者:
Row, Tayur N. Guru
Row, Tayur N. Guru
中科院分区:
化学2区
文献类型:
--
作者:
Kaur, Ramanpreet;Row, Tayur N. Guru

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从一水合没食子酸和乙酰胺的甲醇溶液中生成的多晶无水共晶在完全干燥后转化为稳定形式II,并根据氢键模式的可变性解释了稳定形式的途径,随后进行了理论计算。
Polymorphic anhydrous cocrystals generated from a methanolic solution of gallic acid monohydrate and acetamide are shown to convert to the stable form II on complete drying, and the pathway to the stable form is explained on the basis of the variability in the hydrogen bonding patterns followed by theoretical calculations.